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Cellosaurus UoC-B6 (CVCL_A304)

[Text version]
Cell line name UoC-B6
Synonyms UOC-B6; UOCB6
Accession CVCL_A304
Resource Identification Initiative To cite this cell line use: UoC-B6 (RRID:CVCL_A304)
Comments Population: Caucasian.
Miscellaneous: STR profile from personal communication of Ryan R.J.H.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; 3495; ETV6 + HGNC; 10471; RUNX1; Name(s)=ETV6-RUNX1; TEL-AML1 (PubMed=8704231).
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
B lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1) ETV6-RUNX1 (NCIt: C80334)
B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1) (ORDO: Orphanet_585929)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A297 ! UoC-B4
Sex of cell Female
Age at sampling 3Y6M
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO10,11
D2S133820,25
D3S135816
D5S81812
D7S8208,10
D8S117911,13
D13S31710,12
D16S53911,13
D18S5119
D19S43314,15
D21S1129,30
FGA20,21
TH017,8
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=8231254
Zhang L.Q., Downie P.A., Goodell W.R., McCabe N.R., Le Beau M.M., Morgan R., Sklar J., Raimondi S.C., Miley D., Goldberg A., Lu M.-M., Montag A., Smith S.D.
Establishment of cell lines from B-cell precursor acute lymphoblastic leukemia.
Leukemia 7:1865-1874(1993)

PubMed=8704231; DOI=10.1182/blood.V88.3.785.785
Kim D.-H., Moldwin R.L., Vignon C., Bohlander S.K., Suto Y., Giordano L., Gupta R., Fears S., Nucifora G., Rowley J.D., Smith S.D.
TEL-AML1 translocations with TEL and CDKN2 inactivation in acute lymphoblastic leukemia cell lines.
Blood 88:785-794(1996)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

Cross-references
Encyclopedic resources Wikidata; Q54991260
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number16