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Cellosaurus UoC-B4 (CVCL_A297)

[Text version]
Cell line name UoC-B4
Synonyms UOC-B4; UOCB4; UoCB4
Accession CVCL_A297
Resource Identification Initiative To cite this cell line use: UoC-B4 (RRID:CVCL_A297)
Comments Population: Caucasian.
Derived from site: In situ; Cerebrospinal fluid; UBERON=UBERON_0001359.
Sequence variations
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
B lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1) ETV6-RUNX1 (NCIt: C80334)
B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1) (ORDO: Orphanet_585929)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A304 ! UoC-B6
Sex of cell Female
Age at sampling 3Y6M
Category Cancer cell line
Publications

PubMed=8231254
Li Q. Zhang, Peter A. Downie, William R. Goodell, Norah R. McCabe, Michelle M. Le Beau, Rodman Morgan, Jeffrey Sklar, Susana C. Raimondi, Diane Miley, Aaron Goldberg, Min-Min Lu ...Show all 13 authors... , Anthony Montag, Stephen D. Smith; Show fewer authors
Establishment of cell lines from B-cell precursor acute lymphoblastic leukemia.
Leukemia 7:1865-1874(1993)

PubMed=7630190
Mu-Xiang Zhou, Lu-Bing Gu, Charles David James, J. He, Andrew M. Yeager, Stephen D. Smith, Harry W. Findley Jr.;
Homozygous deletions of the CDKN2 (MTS1/p16ink4) gene in cell lines established from children with acute lymphoblastic leukemia.
Leukemia 9:1159-1161(1995)

PubMed=7849311; DOI=10.1182/blood.V85.4.893.bloodjournal854893
Gail Stranks, Susan E. Height, Paul Mitchell, Dalal Mouneimne Jadayel, Martin A.R. Yuille, Corinne F.M. De Lord, Robyn D. Clutterbuck, Jennie G. Treleaven, Ray Leonard Powles, Elisabeth Nacheva, David G. Oscier ...Show all 17 authors... , Abraham Karpas, Gilbert Marcel Lenoir, Stephen D. Smith, John L. Millar, Daniel Catovsky, Martin John Swinnerton Dyer; Show fewer authors
Deletions and rearrangement of CDKN2 in lymphoid malignancy.
Blood 85:893-901(1995)

PubMed=7888679; DOI=10.1182/blood.V85.6.1608.bloodjournal8561608
Mu-Xiang Zhou, Andrew M. Yeager, Stephen D. Smith, Harry W. Findley Jr.;
Overexpression of the MDM2 gene by childhood acute lymphoblastic leukemia cells expressing the wild-type p53 gene.
Blood 85:1608-1614(1995)

PubMed=8704231; DOI=10.1182/blood.V88.3.785.785
Do-Hyun Kim, Richard L. Moldwin, Clementine Vignon, Stefan Klaus Bohlander, Yoshimasa Suto, Lisa Giordano, Rajat Gupta, Scott Fears, Giuseppina Nucifora, Janet Davison Rowley, Stephen D. Smith;
TEL-AML1 translocations with TEL and CDKN2 inactivation in acute lymphoblastic leukemia cell lines.
Blood 88:785-794(1996)

PubMed=9108419; DOI=10.1182/blood.V89.8.2986
Harry W. Findley Jr., Lu-Bing Gu, Andrew M. Yeager, Mu-Xiang Zhou;
Expression and regulation of Bcl-2, Bcl-xl, and Bax correlate with p53 status and sensitivity to apoptosis in childhood acute lymphoblastic leukemia.
Blood 89:2986-2993(1997)

PubMed=9823951; DOI=10.1038/sj.leu.2401198
Mu-Xiang Zhou, Lu-Bing Gu, Andrew M. Yeager, Harry W. Findley Jr.;
Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression.
Leukemia 12:1756-1763(1998)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Encyclopedic resources Wikidata; Q54991257
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number19