Cellosaurus logo
expasy logo

Cellosaurus HepG2-CYP2E1 (CVCL_A2HH)

[Text][XML][JSON]
Cell line name HepG2-CYP2E1
Accession CVCL_A2HH
Resource Identification Initiative To cite this cell line use: HepG2-CYP2E1 (RRID:CVCL_A2HH)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:2631; CYP2E1.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=14669323; DOI=10.3748/wjg.v9.i12.2732; PMCID=PMC4612042
Jian Zhuge, Ye Luo, Ying-Nian Yu;
Heterologous expression of human cytochrome P450 2E1 in HepG2 cell line.
World J. Gastroenterol. 9:2732-2736(2003)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A2HH
Encyclopedic resources Wikidata; Q105507643
Entry history
Entry creation12-Jan-2021
Last entry update14-Aug-2025
Version number8