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Cellosaurus GC-006-03 (CVCL_A2BE)

[Text version]
Cell line name GC-006-03
Synonyms gc-006-03; gc_006_03
Accession CVCL_A2BE
Resource Identification Initiative To cite this cell line use: GC-006-03 (RRID:CVCL_A2BE)
Comments Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2016152.
Population: Chinese.
Doubling time: 36 hours (PubMed=30271482).
Omics: Genomics; Whole genome sequencing.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Glu33Argfs*20 (c.97delG); Zygosity=Unspecified (PubMed=30271482).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Gly (c.1634A>G); ClinVar=VCV000013656; Zygosity=Unspecified (PubMed=30271482).
Disease Gastric signet ring cell adenocarcinoma (NCIt: C5250)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): CCRID; Patent=CN106367392B

Markers:
AmelogeninX
CSF1PO11,12
D1S165616,17
D2S133818,22
D3S135815
D5S8189,11
D6S104316
D7S82010,11,12 (CCRID)
11,12 (Patent=CN106367392B)
D8S117911,15
D12S39116,17,18,19 (CCRID)
16,17,20 (Patent=CN106367392B)
D13S3178,9
D16S53910,12
D18S5115,16,17 (CCRID)
15,17 (Patent=CN106367392B)
D19S43314
D21S1129,30
FGA23,26
Penta D12
Penta E11,22
TH017,8
TPOX11,12
vWA18,19

Run an STR similarity search on this cell line
Publications

PubMed=30271482; DOI=10.7150/jca.26051; PMCID=PMC6160672
Xin-Yu Su, Yi-Qi Xue, Jing-Sun Wei, Xin-Ying Huo, Yang Gong, Hong-Hong Zhang, Rong-Bo Han, Yue-Tong Chen, Hong Chen, Jin-Fei Chen;
Establishment and characterization of gc-006-03, a novel human signet ring cell gastric cancer cell line derived from metastatic ascites.
J. Cancer 9:3236-3246(2018)

Patent=CN106367392B
Jin-Fei Chen, Yi-Qi Xue, Ling-Zhi Hong, Xin-Ying Huo, Hong Chen, Dong-Ping Wei;
A cancer cell line derived from late gastric signet ring cell and its establishment method and application.
Patent number CN106367392B, 18-Oct-2019

Cross-references
Cell line databases/resources cancercelllines; CVCL_A2BE
CCRID; 1101HUM-PUMC000913
CCRID; 4201PAT-CCTCC00948
Encyclopedic resources Wikidata; Q105506934
Entry history
Entry creation12-Jan-2021
Last entry update10-Apr-2025
Version number8