ID   GC-006-03
AC   CVCL_A2BE
SY   gc-006-03; gc_006_03
DR   cancercelllines; CVCL_A2BE
DR   CCRID; 1101HUM-PUMC000913
DR   CCRID; 4201PAT-CCTCC00948
DR   Wikidata; Q105506934
RX   Patent=CN106367392B;
RX   PubMed=30271482;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2016152.
CC   Population: Chinese.
CC   Doubling time: 36 hours (PubMed=30271482).
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Glu33Argfs*20 (c.97delG); Zygosity=Unspecified (PubMed=30271482).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Gly (c.1634A>G); ClinVar=VCV000013656; Zygosity=Unspecified (PubMed=30271482).
CC   Omics: Genome sequenced.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
ST   Source(s): CCRID; Patent=CN106367392B
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D12S391: 16,17,18,19 (CCRID)
ST   D12S391: 16,17,20 (Patent=CN106367392B)
ST   D13S317: 8,9
ST   D16S539: 10,12
ST   D18S51: 15,16,17 (CCRID)
ST   D18S51: 15,17 (Patent=CN106367392B)
ST   D19S433: 14
ST   D1S1656: 16,17
ST   D21S11: 29,30
ST   D2S1338: 18,22
ST   D3S1358: 15
ST   D5S818: 9,11
ST   D6S1043: 16
ST   D7S820: 10,11,12 (CCRID)
ST   D7S820: 11,12 (Patent=CN106367392B)
ST   D8S1179: 11,15
ST   FGA: 23,26
ST   Penta D: 12
ST   Penta E: 11,22
ST   TH01: 7,8
ST   TPOX: 11,12
ST   vWA: 18,19
DI   NCIt; C5250; Gastric signet ring cell adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   55Y
CA   Cancer cell line
DT   Created: 12-01-21; Last updated: 05-10-23; Version: 6
//
RX   Patent=CN106367392B;
RA   Chen J.-F., Xue Y.-Q., Hong L.-Z., Huo X.-Y., Chen H., Wei D.-P.;
RT   "A cancer cell line derived from late gastric signet ring cell and its
RT   establishment method and application.";
RL   Patent number CN106367392B, 18-Oct-2019.
//
RX   PubMed=30271482; DOI=10.7150/jca.26051;
RA   Su X.-Y., Xue Y.-Q., Wei J.-S., Huo X.-Y., Gong Y., Zhang H.-H.,
RA   Han R.-B., Chen Y.-T., Chen H., Chen J.-F.;
RT   "Establishment and characterization of gc-006-03, a novel human signet
RT   ring cell gastric cancer cell line derived from metastatic ascites.";
RL   J. Cancer 9:3236-3246(2018).
//