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Cellosaurus CHRF-288-11 (CVCL_A280)

[Text version]
Cell line name CHRF-288-11
Synonyms CHRF288-11; CHRF-288
Accession CVCL_A280
Resource Identification Initiative To cite this cell line use: CHRF-288-11 (RRID:CVCL_A280)
Comments Population: Caucasian.
Characteristics: Established from a nude mouse xenograft.
Doubling time: ~33 hours (PubMed=2310825).
Omics: Transcriptomics; Microarray.
Misspelling: CHRF-28-11; Note=Occasionally.
Derived from site: Metastatic; Eye socket; UBERON=UBERON_0001697.
Disease Childhood acute megakaryoblastic leukemia (NCIt: C7972)
Acute megakaryoblastic leukemia (ORDO: Orphanet_518)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 1Y6M
Category Cancer cell line
Publications

PubMed=3719517; DOI=10.1002/1097-0142(19860715)58:2<238::AID-CNCR2820580207>3.0.CO;2-#
Witte D.P., Harris R.E., Jenski L.J., Lampkin B.C.
Megakaryoblastic leukemia in an infant. Establishment of a megakaryocytic tumor cell line in athymic nude mice.
Cancer 58:238-244(1986)

PubMed=2310825; DOI=10.1182/blood.V75.6.1252.1252
Fugman D.A., Witte D.P., Jones C.L.A., Aronow B.J., Lieberman M.A.
In vitro establishment and characterization of a human megakaryoblastic cell line.
Blood 75:1252-1261(1990)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=17309828; DOI=10.1016/j.exphem.2006.10.017
Fuhrken P.G., Chen C., Miller W.M., Papoutsakis E.T.
Comparative, genome-scale transcriptional analysis of CHRF-288-11 and primary human megakaryocytic cell cultures provides novel insights into lineage-specific differentiation.
Exp. Hematol. 35:476-489(2007)

PubMed=27277069; DOI=10.1160/TH15-11-0891; PMCID=PMC5080539
Wright J.R., Amisten S., Goodall A.H., Mahaut-Smith M.P.
Transcriptomic analysis of the ion channelome of human platelets and megakaryocytic cell lines.
Thromb. Haemost. 116:272-284(2016)

Cross-references
Encyclopedic resources Wikidata; Q54813288
Experimental variables resources EFO; EFO_0022520
Gene expression databases GEO; GSE3838
Polymorphism and mutation databases Cosmic; 787422
Cosmic; 975240
Cosmic; 1050595
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number18