ID   CHRF-288-11
AC   CVCL_A280
SY   CHRF288-11; CHRF-288
DR   EFO; EFO_0022520
DR   Cosmic; 787422
DR   Cosmic; 975240
DR   Cosmic; 1050595
DR   GEO; GSE3838
DR   Wikidata; Q54813288
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=2310825;
RX   PubMed=3719517;
RX   PubMed=17309828;
RX   PubMed=27277069;
CC   Population: Caucasian.
CC   Characteristics: Established from a nude mouse xenograft.
CC   Doubling time: ~33 hours (PubMed=2310825).
CC   Omics: Transcriptomics; Microarray.
CC   Misspelling: CHRF-28-11; Note=Occasionally.
CC   Derived from site: Metastatic; Eye socket; UBERON=UBERON_0001697.
DI   NCIt; C7972; Childhood acute megakaryoblastic leukemia
DI   ORDO; Orphanet_518; Acute megakaryoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   1Y6M
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-04-25; Version: 18
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=2310825; DOI=10.1182/blood.V75.6.1252.1252;
RA   Fugman D.A., Witte D.P., Jones C.L.A., Aronow B.J., Lieberman M.A.;
RT   "In vitro establishment and characterization of a human
RT   megakaryoblastic cell line.";
RL   Blood 75:1252-1261(1990).
//
RX   PubMed=3719517; DOI=10.1002/1097-0142(19860715)58:2<238::AID-CNCR2820580207>3.0.CO;2-#;
RA   Witte D.P., Harris R.E., Jenski L.J., Lampkin B.C.;
RT   "Megakaryoblastic leukemia in an infant. Establishment of a
RT   megakaryocytic tumor cell line in athymic nude mice.";
RL   Cancer 58:238-244(1986).
//
RX   PubMed=17309828; DOI=10.1016/j.exphem.2006.10.017;
RA   Fuhrken P.G., Chen C., Miller W.M., Papoutsakis E.T.;
RT   "Comparative, genome-scale transcriptional analysis of CHRF-288-11 and
RT   primary human megakaryocytic cell cultures provides novel insights
RT   into lineage-specific differentiation.";
RL   Exp. Hematol. 35:476-489(2007).
//
RX   PubMed=27277069; DOI=10.1160/TH15-11-0891; PMCID=PMC5080539;
RA   Wright J.R., Amisten S., Goodall A.H., Mahaut-Smith M.P.;
RT   "Transcriptomic analysis of the ion channelome of human platelets and
RT   megakaryocytic cell lines.";
RL   Thromb. Haemost. 116:272-284(2016).
//