Cellosaurus cell line ABC-14 (CVCL

Cross-references
Cell line name	ABC-14
Accession	CVCL_A1EF
Resource Identification Initiative	To cite this cell line use: ABC-14 (RRID:CVCL_A1EF)
Comments	Population: Japanese. Characteristics: Sensitive to crizotinib and resistant to alectinib. Omics: Transcriptomics; RNAseq. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Gene fusion; HGNC; HGNC:427; ALK + HGNC; HGNC:1316; EML4; Name(s)=EML4-ALK (PubMed=31374369).
Disease	Lung adenocarcinoma (NCIt: C3512)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_A1EG ! ABC-17
Sex of cell	Male
Age at sampling	51Y
Category	Cancer cell line
Publications	PubMed=31374369; DOI=10.1016/j.jtho.2019.07.017 Go Makimoto, Kadoaki Ohashi, Shuta Tomida, Kazuya Nishii, Takehiro Matsubara, Hiroe Kayatani, Hisao Higo, Kiichiro Ninomiya, Akiko Sato, Hiromi Watanabe, Hirohisa Kano ...Show all 21 authors... , Takashi Ninomiya, Toshio Kubo, Kammei Rai, Eiki Ichihara, Katsuyuki Hotta, Masahiro Tabata, Shinichi Toyooka, Minoru Takata, Yoshinobu Maeda, Katsuyuki Kiura; Show fewer authors Rapid acquisition of alectinib resistance in ALK-positive lung cancer with high tumor mutation burden. J. Thorac. Oncol. 14:2009-2018(2019)
Encyclopedic resources	Wikidata; Q102113498
Polymorphism and mutation databases	Cosmic; 2843080
Entry history
Entry creation	29-Oct-2020
Last entry update	10-Apr-2025
Version number	7