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Cellosaurus HEPC-CB.1 (CVCL_A1AV)

[Text version]
Cell line name HEPC-CB.1
Synonyms HucPEC 55.1; Human Endothelial Progenitor Cells-Cord Blood.1
Accession CVCL_A1AV
Resource Identification Initiative To cite this cell line use: HEPC-CB.1 (RRID:CVCL_A1AV)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-4220.
Characteristics: Expresses CD133 and CD271, markers specific for early stem/progenitor cells. Can undergo an in vitro pre-angiogenic process, forms pseudovessel structures and presents an accelerated angiogenesis in hypoxic conditions (PubMed=21710642).
Transfected with: HGNC; 11730; TERT.
Miscellaneous: Sex of donor from personal communication of Kieda C.
Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168.
Cell type: Endothelial progenitor cell; CL=CL_0002546.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A1AW ! HEPC-CB.2
Sex of cell Female
Age at sampling <1D
Category Telomerase immortalized cell line
Publications

PubMed=21710642; DOI=10.1002/cyto.a.21092
Paprocka M., Krawczenko A., Dus D., Kantor A., Carreau A., Grillon C., Kieda C.
CD133 positive progenitor endothelial cell lines from human cord blood.
Cytometry A 79:594-602(2011)

Patent=US9631178
Kieda C., Grillon C., Lamerant-Fayel N., Paprocka M., Krawczenko A., Dus D.
Human and murine stem-cell lines: models of endothelial cell precursors.
Patent number US9631178, 25-Apr-2017

PubMed=32705508; DOI=10.1007/s11033-020-05662-6
Kantor A., Krawczenko A., Bielawska-Pohl A., Dus D., Grillon C., Kieda C., Charkiewicz K., Paprocka M.
Activity of the human immortalized endothelial progenitor cell line HEPC-CB.1 supporting in vitro angiogenesis.
Mol. Biol. Rep. 47:5911-5925(2020)

Cross-references
Encyclopedic resources Wikidata; Q102114122
Entry history
Entry creation29-Oct-2020
Last entry update29-Jun-2023
Version number6