Cellosaurus logo
expasy logo

Cellosaurus HEPC-CB.1 (CVCL_A1AV)

[Text version]
Cell line name HEPC-CB.1
Synonyms HucPEC 55.1; Human Endothelial Progenitor Cells-Cord Blood.1
Accession CVCL_A1AV
Resource Identification Initiative To cite this cell line use: HEPC-CB.1 (RRID:CVCL_A1AV)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-4220.
Characteristics: Expresses CD133 and CD271, markers specific for early stem/progenitor cells. Can undergo an in vitro pre-angiogenic process, forms pseudovessel structures and presents an accelerated angiogenesis in hypoxic conditions (PubMed=21710642).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Miscellaneous: Sex of donor from personal communication of Kieda, Claudine.
Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168.
Cell type: Endothelial progenitor cell; CL=CL_0002546.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A1AW ! HEPC-CB.2
Sex of cell Female
Age at sampling <1D
Category Telomerase immortalized cell line
Publications

PubMed=21710642; DOI=10.1002/cyto.a.21092
Maria Paprocka, Agnieszka Krawczenko, Danuta Dus, Aneta Kantor, Aude Carreau, Catherine Grillon, Claudine Kieda;
CD133 positive progenitor endothelial cell lines from human cord blood.
Cytometry A 79:594-602(2011)

Patent=US9631178
Claudine Kieda, Catherine Grillon, Nathalie Lamerant-Fayel, Maria Paprocka, Agnieszka Krawczenko, Danuta Dus;
Human and murine stem-cell lines: models of endothelial cell precursors.
Patent number US9631178, 25-Apr-2017

PubMed=32705508; DOI=10.1007/s11033-020-05662-6; PMCID=PMC7455590
Aneta Kantor, Agnieszka Krawczenko, Aleksandra Bielawska-Pohl, Danuta Dus, Catherine Grillon, Claudine Kieda, Karol Charkiewicz, Maria Paprocka;
Activity of the human immortalized endothelial progenitor cell line HEPC-CB.1 supporting in vitro angiogenesis.
Mol. Biol. Rep. 47:5911-5925(2020)

Cross-references
Encyclopedic resources Wikidata; Q102114122
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number8