ID   HEPC-CB.1
AC   CVCL_A1AV
SY   HucPEC 55.1; Human Endothelial Progenitor Cells-Cord Blood.1
DR   Wikidata; Q102114122
RX   Patent=US9631178;
RX   PubMed=21710642;
RX   PubMed=32705508;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-4220.
CC   Characteristics: Expresses CD133 and CD271, markers specific for early stem/progenitor cells. Can undergo an in vitro pre-angiogenic process, forms pseudovessel structures and presents an accelerated angiogenesis in hypoxic conditions (PubMed=21710642).
CC   Transfected with: HGNC; 11730; TERT.
CC   Miscellaneous: Sex of donor from personal communication of Kieda C.
CC   Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168.
CC   Cell type: Endothelial progenitor cell; CL=CL_0002546.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_A1AW ! HEPC-CB.2
SX   Female
AG   <1D
CA   Telomerase immortalized cell line
DT   Created: 29-10-20; Last updated: 29-06-23; Version: 6
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RX   Patent=US9631178;
RA   Kieda C., Grillon C., Lamerant-Fayel N., Paprocka M., Krawczenko A.,
RA   Dus D.;
RT   "Human and murine stem-cell lines: models of endothelial cell
RT   precursors.";
RL   Patent number US9631178, 25-Apr-2017.
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RX   PubMed=21710642; DOI=10.1002/cyto.a.21092;
RA   Paprocka M., Krawczenko A., Dus D., Kantor A., Carreau A., Grillon C.,
RA   Kieda C.;
RT   "CD133 positive progenitor endothelial cell lines from human cord
RT   blood.";
RL   Cytometry A 79:594-602(2011).
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RX   PubMed=32705508; DOI=10.1007/s11033-020-05662-6;
RA   Kantor A., Krawczenko A., Bielawska-Pohl A., Dus D., Grillon C.,
RA   Kieda C., Charkiewicz K., Paprocka M.;
RT   "Activity of the human immortalized endothelial progenitor cell line
RT   HEPC-CB.1 supporting in vitro angiogenesis.";
RL   Mol. Biol. Rep. 47:5911-5925(2020).
//