ID   HEPC-CB.1
AC   CVCL_A1AV
SY   HucPEC 55.1; Human Endothelial Progenitor Cells-Cord Blood.1
DR   Wikidata; Q102114122
RX   Patent=US9631178;
RX   PubMed=21710642;
RX   PubMed=32705508;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-4220.
CC   Characteristics: Expresses CD133 and CD271, markers specific for early stem/progenitor cells. Can undergo an in vitro pre-angiogenic process, forms pseudovessel structures and presents an accelerated angiogenesis in hypoxic conditions (PubMed=21710642).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Miscellaneous: Sex of donor from personal communication of Kieda, Claudine.
CC   Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168.
CC   Cell type: Endothelial progenitor cell; CL=CL_0002546.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_A1AW ! HEPC-CB.2
SX   Female
AG   <1D
CA   Telomerase immortalized cell line
DT   Created: 29-10-20; Last updated: 19-12-24; Version: 8
//
RX   PubMed=21710642; DOI=10.1002/cyto.a.21092;
RA   Paprocka, Maria
RA   Krawczenko, Agnieszka
RA   Dus, Danuta
RA   Kantor, Aneta
RA   Carreau, Aude
RA   Grillon, Catherine
RA   Kieda, Claudine
RT   "CD133 positive progenitor endothelial cell lines from human cord
RT   blood.";
RL   Cytometry A 79:594-602(2011).
//
RX   Patent=US9631178;
RA   Kieda, Claudine
RA   Grillon, Catherine
RA   Lamerant-Fayel, Nathalie
RA   Paprocka, Maria
RA   Krawczenko, Agnieszka
RA   Dus, Danuta
RT   "Human and murine stem-cell lines: models of endothelial cell
RT   precursors.";
RL   Patent number US9631178, 25-Apr-2017.
//
RX   PubMed=32705508; DOI=10.1007/s11033-020-05662-6; PMCID=PMC7455590;
RA   Kantor, Aneta
RA   Krawczenko, Agnieszka
RA   Bielawska-Pohl, Aleksandra
RA   Dus, Danuta
RA   Grillon, Catherine
RA   Kieda, Claudine
RA   Charkiewicz, Karol
RA   Paprocka, Maria
RT   "Activity of the human immortalized endothelial progenitor cell line
RT   HEPC-CB.1 supporting in vitro angiogenesis.";
RL   Mol. Biol. Rep. 47:5911-5925(2020).
//