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Cellosaurus Ma-Mel-08b (CVCL_A122)

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Cell line name Ma-Mel-08b
Synonyms Ma-Mel_08b; Ma-Mel-8b
Accession CVCL_A122
Resource Identification Initiative To cite this cell line use: Ma-Mel-08b (RRID:CVCL_A122)
Comments Omics: Transcriptomics; Microarray.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Cutaneous nodular melanoma (NCIt: C4225)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A121 ! Ma-Mel-08a
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-190

Markers:
AmelogeninX
CSF1PO11,12
D3S135815
D5S81812,13
D7S82010
D13S31712
FGA21
TH019.3
TPOX8
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Keith S. Hoek, Natalie C. Schlegel, Patricia Brafford, Antje Sucker, Selma Ugurel, Rajiv Kumar, Barbara L. Weber, Katherine L. Nathanson, Donald J. Phillips, Meenhard Herlyn, Dirk Schadendorf, Reinhard Dummer;
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=23348503; DOI=10.1126/science.1230062
Susanne Horn, Adina Figl, P. Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar;
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources ESTDAB; ESTDAB-190
Encyclopedic resources Wikidata; Q54903731
Gene expression databases GEO; GSM109053
Polymorphism and mutation databases Cosmic; 1846567
Cosmic; 2686332
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number16