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Cellosaurus ZMAC-4 (CVCL_A0XV)

[Text version]
Cell line name ZMAC-4
Synonyms ZMAC1107-4; Zuckermann MACrophage-4
Accession CVCL_A0XV
Resource Identification Initiative To cite this cell line use: ZMAC-4 (RRID:CVCL_A0XV)
Comments Characteristics: CSF1 dependent.
Virology: Susceptible to infection by porcine reproductive and respiratory syndrome virus (PRRSV) (PubMed=21191013).
Virology: Supports high level of replication of African swine fever virus attenuated strain OURT88/3 (PubMed=32515659).
Doubling time: 3.9 +- 0.3 days (PubMed=32515659).
Derived from site: In situ; Fetal lung, alveolus; UBERON=UBERON_0005597+UBERON_0002299.
Cell type: Alveolar macrophage; CL=CL_0000583.
Species of origin Sus scrofa (Pig) (NCBI Taxonomy: 9823)
Breed/subspecies: Landrace x Yorkshire x Duroc.
Sex of cell Sex unspecified
Age at sampling 60FD
Category Factor-dependent cell line

PubMed=21191013; DOI=10.1128/JVI.01616-10
Calzada-Nova G., Schnitzlein W.M., Husmann R.J., Zuckermann F.A.
North American porcine reproductive and respiratory syndrome viruses inhibit type I interferon production by plasmacytoid dendritic cells.
J. Virol. 85:2703-2713(2011)

Zuckermann F.A.
Non-simian cells for growth of porcine reproductive and respiratory syndrome (PRRS) virus.
Patent number US9169465, 27-Oct-2015

PubMed=32515659; DOI=10.1080/22221751.2020.1772675
Portugal R., Goatley L.C., Husmann R.J., Zuckermann F.A., Dixon L.K.
A porcine macrophage cell line that supports high levels of replication of OURT88/3, an attenuated strain of African swine fever virus.
Emerg. Microbes Infect. 9:1245-1253(2020)

Encyclopedic resources Wikidata; Q108821563
Entry history
Entry creation23-Sep-2021
Last entry update29-Jun-2023
Version number6