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Cellosaurus UT-SCC-60A (CVCL_A089)

[Text version]
Cell line name UT-SCC-60A
Synonyms UT-SCC 60 A; University of Turku-Squamous Cell Carcinoma-60A
Accession CVCL_A089
Resource Identification Initiative To cite this cell line use: UT-SCC-60A (RRID:CVCL_A089)
Comments Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Derived from site: In situ; Oral cavity, tonsil; UBERON=UBERON_0002372.
Sequence variations
Disease Tonsillar squamous cell carcinoma (NCIt: C8183)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A090 ! UT-SCC-60B
Sex of cell Male
Age at sampling 59Y
Category Cancer cell line
STR profile Source(s): PubMed=30135316

Markers:
AmelogeninX
CSF1PO11
D2S133817,25
D3S135816
D5S81812
D7S8209,10
D8S11799,13
D13S31711,12
D16S5399,12
D18S5112,16
D19S43313,16
D21S1130.2
FGA20,21
TH018,9
TPOX8
vWA18,19

Run an STR similarity search on this cell line
Publications

PubMed=15287027; DOI=10.1002/gcc.20066
Satoru Takebayashi, Arthur Hickson, Tetsuya Ogawa, Kwang-Yoon Jung, Hiroyuki Mineta, Yo Ueda, Reidar Grenman, Susan G. Fisher, Thomas E. Carey;
Loss of chromosome arm 18q with tumor progression in head and neck squamous cancer.
Genes Chromosomes Cancer 41:145-154(2004)

PubMed=29970484; DOI=10.1158/1535-7163.MCT-17-0733
Tatiana Lepikhova, Piia-Riitta Karhemo, Riku Louhimo, Bhagwan Yadav, Astrid Murumagi, Evgeny Kulesskiy, Mikko Kivento, Harri Sihto, Reidar Grenman, Stina M. Syrjanen, Olli-Pekka Kallioniemi ...Show all 15 authors... , Tero Aittokallio, Krister Wennerberg, Heikki Joensuu, Outi Monni; Show fewer authors
Drug-sensitivity screening and genomic characterization of 45 HPV-negative head and neck carcinoma cell lines for novel biomarkers of drug efficacy.
Mol. Cancer Ther. 17:2060-2071(2018)

PubMed=30135316; DOI=10.1172/jci.insight.122204; PMCID=PMC6141174
Stephen M.F. Jamieson, Peter Tsai, Maria K. Kondratyev, Pratha Budhani, Arthur Liu, Neil N. Senzer, E. Gabriela Chiorean, Shadia I. Jalal, John Joseph Nemunaitis, Dennis Kee, Avik Shome ...Show all 35 authors... , Way W. Wong, Dan Li, Nooriyah Poonawala-Lohani, Purvi M. Kakadia, Nicholas S. Knowlton, Courtney R.H. Lynch, Cho R. Hong, Tet Woo Lee, Reidar Grenman, Laura Caporiccio, Trevor David McKee, Mark Zaidi, Sehrish Butt, Andrew M.J. Macann, Nicholas P. McIvor, John M. Chaplin, Kevin O. Hicks, Stefan Klaus Bohlander, Bradly G. Wouters, Charles P. Hart, Cristin Gregor Print, William R. Wilson, Michael A. Curran, Francis W. Hunter; Show fewer authors
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.
JCI Insight 3:e122204.1-e122204.19(2018)

DOI=10.1158/1538-7445.AM2020-507
Maria K. Kondratyev, Aleksandra Pesic, Anna Dvorkin-Sheva, Troy Ketela, Jason Moffat, Marianne Koritzinsky, Bradly G. Wouters;
Repurposing of FDA approved drugs for treatment of metastatic HNSCC.
Cancer Res. 80 Suppl. 16:507-507(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A089
Encyclopedic resources Wikidata; Q54992182
Gene expression databases GEO; GSM2883380
GEO; GSM2888843
Polymorphism and mutation databases Cosmic; 1140776
Cosmic; 1219860
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number13