ID   UT-SCC-60A
AC   CVCL_A089
SY   UT-SCC 60 A; University of Turku-Squamous Cell Carcinoma-60A
DR   cancercelllines; CVCL_A089
DR   Cosmic; 1140776
DR   Cosmic; 1219860
DR   GEO; GSM2883380
DR   GEO; GSM2888843
DR   Wikidata; Q54992182
RX   DOI=10.1158/1538-7445.AM2020-507;
RX   PubMed=15287027;
RX   PubMed=29970484;
RX   PubMed=30135316;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg342Ter (c.1024C>T); ClinVar=VCV000182970; Zygosity=Homozygous (PubMed=29970484).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; Array-based CGH.
CC   Derived from site: In situ; Oral cavity, tonsil; UBERON=UBERON_0002372.
ST   Source(s): PubMed=30135316
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11,12
ST   D16S539: 9,12
ST   D18S51: 12,16
ST   D19S433: 13,16
ST   D21S11: 30.2
ST   D2S1338: 17,25
ST   D3S1358: 16
ST   D5S818: 12
ST   D7S820: 9,10
ST   D8S1179: 9,13
ST   FGA: 20,21
ST   TH01: 8,9
ST   TPOX: 8
ST   vWA: 18,19
DI   NCIt; C8183; Tonsillar squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_A090 ! UT-SCC-60B
SX   Male
AG   59Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-04-25; Version: 13
//
RX   PubMed=29970484; DOI=10.1158/1535-7163.MCT-17-0733;
RA   Lepikhova, Tatiana
RA   Karhemo, Piia-Riitta
RA   Louhimo, Riku
RA   Yadav, Bhagwan
RA   Murumagi, Astrid
RA   Kulesskiy, Evgeny
RA   Kivento, Mikko
RA   Sihto, Harri
RA   Grenman, Reidar
RA   Syrjanen, Stina M.
RA   Kallioniemi, Olli-Pekka
RA   Aittokallio, Tero
RA   Wennerberg, Krister
RA   Joensuu, Heikki
RA   Monni, Outi
RT   "Drug-sensitivity screening and genomic characterization of 45
RT   HPV-negative head and neck carcinoma cell lines for novel biomarkers
RT   of drug efficacy.";
RL   Mol. Cancer Ther. 17:2060-2071(2018).
//
RX   PubMed=15287027; DOI=10.1002/gcc.20066;
RA   Takebayashi, Satoru
RA   Hickson, Arthur
RA   Ogawa, Tetsuya
RA   Jung, Kwang-Yoon
RA   Mineta, Hiroyuki
RA   Ueda, Yo
RA   Grenman, Reidar
RA   Fisher, Susan G.
RA   Carey, Thomas E.
RT   "Loss of chromosome arm 18q with tumor progression in head and neck
RT   squamous cancer.";
RL   Genes Chromosomes Cancer 41:145-154(2004).
//
RX   PubMed=30135316; DOI=10.1172/jci.insight.122204; PMCID=PMC6141174;
RA   Jamieson, Stephen M.F.
RA   Tsai, Peter
RA   Kondratyev, Maria K.
RA   Budhani, Pratha
RA   Liu, Arthur
RA   Senzer, Neil N.
RA   Chiorean, E. Gabriela
RA   Jalal, Shadia I.
RA   Nemunaitis, John Joseph
RA   Kee, Dennis
RA   Shome, Avik
RA   Wong, Way W.
RA   Li, Dan
RA   Poonawala-Lohani, Nooriyah
RA   Kakadia, Purvi M.
RA   Knowlton, Nicholas S.
RA   Lynch, Courtney R.H.
RA   Hong, Cho R.
RA   Lee, Tet Woo
RA   Grenman, Reidar
RA   Caporiccio, Laura
RA   McKee, Trevor David
RA   Zaidi, Mark
RA   Butt, Sehrish
RA   Macann, Andrew M.J.
RA   McIvor, Nicholas P.
RA   Chaplin, John M.
RA   Hicks, Kevin O.
RA   Bohlander, Stefan Klaus
RA   Wouters, Bradly G.
RA   Hart, Charles P.
RA   Print, Cristin Gregor
RA   Wilson, William R.
RA   Curran, Michael A.
RA   Hunter, Francis W.
RT   "Evofosfamide for the treatment of human papillomavirus-negative head
RT   and neck squamous cell carcinoma.";
RL   JCI Insight 3:e122204.1-e122204.19(2018).
//
RX   DOI=10.1158/1538-7445.AM2020-507;
RA   Kondratyev, Maria K.
RA   Pesic, Aleksandra
RA   Dvorkin-Sheva, Anna
RA   Ketela, Troy
RA   Moffat, Jason
RA   Koritzinsky, Marianne
RA   Wouters, Bradly G.
RT   "Repurposing of FDA approved drugs for treatment of metastatic HNSCC.";
RL   Cancer Res. 80 Suppl. 16:507-507(2020).
//