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Cellosaurus NHEK/SVTERT3-5 (CVCL_9Q51)

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Cell line name NHEK/SVTERT3-5
Accession CVCL_9Q51
Resource Identification Initiative To cite this cell line use: NHEK/SVTERT3-5 (RRID:CVCL_9Q51)
Comments Doubling time: 48-60 hours (Evercyte=CLHT-011-0026-5).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Miscellaneous: STR profile from personal communication of Evercyte.
Derived from site: In situ; Abdomen, skin, epidermis; UBERON=UBERON_0001416+UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9Q50 (NHEK/SV3)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): Evercyte=CLHT-011-0026-5

Markers:
CSF1PO11,12
D5S8187,12
D7S82010,12
D13S3178,12
D16S5399,13
TH019
TPOX8,9
vWA16,17

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Publications

PubMed=28776197; DOI=10.1007/s00204-017-2034-6; PMCID=PMC5773649
Regina Weinmuellner, Kushtrim Kryeziu, Barbara Zbiral, Koray Tav, Beatrix Schoenhacker-Alte, Daniela Groza, Laurin R. Wimmer, Markus Schosserer, Fabian Nagelreiter, Stefanie Rosinger, Michael Mildner ...Show all 15 authors... , Erwin Tschachler, Michael Grusch, Johannes Grillari, Petra Heffeter; Show fewer authors
Long-term exposure of immortalized keratinocytes to arsenic induces EMT, impairs differentiation in organotypic skin models and mimics aspects of human skin derangements.
Arch. Toxicol. 92:181-194(2018)

Cross-references
Cell line collections (Providers) Evercyte; CLHT-011-0026-5
Encyclopedic resources Wikidata; Q54930514
Entry history
Entry creation23-Feb-2016
Last entry update14-Aug-2025
Version number13