ID   NHEK/SVTERT3-5
AC   CVCL_9Q51
DR   Evercyte; CLHT-011-0026-5
DR   Wikidata; Q54930514
RX   PubMed=28776197;
CC   Doubling time: 48-60 hours (Evercyte=CLHT-011-0026-5).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Miscellaneous: STR profile from personal communication of Evercyte.
CC   Derived from site: In situ; Abdomen, skin, epidermis; UBERON=UBERON_0001416+UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
ST   Source(s): Evercyte=CLHT-011-0026-5
ST   CSF1PO: 11,12
ST   D13S317: 8,12
ST   D16S539: 9,13
ST   D5S818: 7,12
ST   D7S820: 10,12
ST   TH01: 9
ST   TPOX: 8,9
ST   vWA: 16,17
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_9Q50 ! NHEK/SV3
SX   Female
AG   Age unspecified
CA   Transformed cell line
DT   Created: 23-02-16; Last updated: 10-04-25; Version: 12
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RX   PubMed=28776197; DOI=10.1007/s00204-017-2034-6; PMCID=PMC5773649;
RA   Weinmuellner R., Kryeziu K., Zbiral B., Tav K., Schoenhacker-Alte B.,
RA   Groza D., Wimmer L.R., Schosserer M., Nagelreiter F., Rosinger S.,
RA   Mildner M., Tschachler E., Grusch M., Grillari J., Heffeter P.;
RT   "Long-term exposure of immortalized keratinocytes to arsenic induces
RT   EMT, impairs differentiation in organotypic skin models and mimics
RT   aspects of human skin derangements.";
RL   Arch. Toxicol. 92:181-194(2018).
//