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Cellosaurus IOR/OS10 (CVCL_9989)

[Text version]
Cell line name IOR/OS10
Synonyms IOR-OS10; OS-10; OS10
Accession CVCL_9989
Resource Identification Initiative To cite this cell line use: IOR/OS10 (RRID:CVCL_9989)
Comments From: Laboratorio di Ricerca Oncologica, Istituti Ortopedici Rizzoli; Bologna; Italy.
Doubling time: ~72 hours (PubMed=21519327).
Omics: Variations; SNP array analysis.
Derived from site: In situ; Bone; UBERON=UBERON_0002481.
Sequence variations
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 10Y
Category Cancer cell line
STR profile Source(s): PubMed=19787792

Markers:
AmelogeninX
D2S133826
D3S135815,16
D5S81813
D8S117911
D16S53913
D18S5112
D19S43314,15
D21S1129,30
FGA21.2,23
SE3316,23.2
TH016
TPOX9,10
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=8617485; DOI=10.1016/S0046-8177(96)90115-X
Katia Scotlandi, Massimo Serra, Maria Cristina Manara, Stefania Benini, Manuela Sarti, Daniela Maurici, Pier-Luigi Lollini, Piero Picci, Francesco Bertoni, Nicola Baldini;
Immunostaining of the p30/32MIC2 antigen and molecular detection of EWS rearrangements for the diagnosis of Ewing's sarcoma and peripheral neuroectodermal tumor.
Hum. Pathol. 27:408-416(1996)

PubMed=9935160; DOI=10.1002/(SICI)1097-0215(19990209)80:4<581::AID-IJC16>3.0.CO;2-O
Stefania Benini, Nicola Baldini, Maria Cristina Manara, Tokuhiro Chano, Massimo Serra, Simona Rizzi, Pier-Luigi Lollini, Piero Picci, Katia Scotlandi;
Redundancy of autocrine loops in human osteosarcoma cells.
Int. J. Cancer 80:581-588(1999)

PubMed=19787792; DOI=10.1002/gcc.20717
Laura Ottaviano, Karl-Ludwig Schaefer, Melanie Gajewski, Wolfgang Huckenbeck, Stefan E. Baldus, Uwe Rogel, Carlos Mackintosh, Enrique de Alava, Ola Myklebost, Stine Henrichson Kresse, Leonardo Andres Meza-Zepeda ...Show all 18 authors... , Massimo Serra, Anne-Marie Cleton-Jansen, Pancras Cornelis Wilhelmus Hogendoorn, Horst Buerger, Thomas Aigner, Helmut Erich Gabbert, Christopher Poremba; Show fewer authors
Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort.
Genes Chromosomes Cancer 49:40-51(2010)

PubMed=21519327; DOI=10.1038/labinvest.2011.72
Alexander B. Mohseny, Isidro Machado, Yong-Ping Cai, Karl-Ludwig Schaefer, Massimo Serra, Pancras Cornelis Wilhelmus Hogendoorn, Antonio Llombart-Bosch, Anne-Marie Cleton-Jansen;
Functional characterization of osteosarcoma cell lines provides representative models to study the human disease.
Lab. Invest. 91:1195-1205(2011)

PubMed=23144859; DOI=10.1371/journal.pone.0048262; PMCID=PMC3492335
Stine Henrichson Kresse, Halfdan Rydbeck, Magne Skarn, Heidi Maria Namlos, Ana Heslanyeth Barragan-Polania, Anne-Marie Cleton-Jansen, Massimo Serra, Knut Liestol, Pancras Cornelis Wilhelmus Hogendoorn, Eivind Hovig, Ola Myklebost, Leonardo Andres Meza-Zepeda;
Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma.
PLoS ONE 7:e48262.1-e48262.20(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_9989
Encyclopedic resources Wikidata; Q54897868
Gene expression databases GEO; GSM879210
Polymorphism and mutation databases Cosmic; 1082498
Cosmic; 1529913
IARC_TP53; 27022
Progenetix; CVCL_9989
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number20