| Cell line name |
GLAG-66 |
| Accession |
CVCL_9918 |
| Resource Identification Initiative |
To cite this cell line use: GLAG-66 (RRID:CVCL_9918) |
| Comments |
Population: Caucasian; Italian. Derived from site: Metastatic; Thyroid gland; UBERON=UBERON_0002046. |
| Sequence variations |
- Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from child cell line K1).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu542Lys (c.1624G>A); ClinVar=VCV000031944; Zygosity=Heterozygous (from child cell line K1).
- Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Heterozygous; Note=In promoter (from child cell line K1).
|
| Disease |
Thyroid gland papillary carcinoma (NCIt: C4035) Differentiated thyroid carcinoma (ORDO: Orphanet_146) |
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
| Hierarchy |
Children:
|
| Sex of cell |
Male |
| Age at sampling |
58Y |
| Category |
Cancer cell line |
| Publications | PubMed=8330267; DOI=10.1016/0165-4608(93)90163-G Patrick Antonini, Gustavo Linares, Nadine Gaillard, Anne-Marie Venuat, Martin Schlumberger, Jean-Paul Travagli, Bernard Caillou, Roland Berger, Claude Parmentier; Cytogenetic characterization of a new human papillary thyroid carcinoma permanent cell line (GLAG-66). Cancer Genet. Cytogenet. 67:117-122(1993) PubMed=19087340; DOI=10.1186/1471-2407-8-371; PMCID=PMC2651892 Franclim Ricardo Ribeiro, Ana Margarida Meireles, Ana Sofia Rocha, Manuel R. Teixeira; Conventional and molecular cytogenetics of human non-medullary thyroid carcinoma: characterization of eight cell line models and review of the literature on clinical samples. BMC Cancer 8:371.1-371.11(2008) |
| Cross-references |
| Cell line databases/resources |
cancercelllines; CVCL_9918
|
| Anatomy/cell type resources |
BTO; BTO_0006406
|
| Encyclopedic resources |
Wikidata; Q54835892
|
| Entry history |
| Entry creation | 06-Jun-2012 |
| Last entry update | 19-Dec-2024 |
| Version number | 20 |
|---|