Cellosaurus logo
expasy logo

Cellosaurus GLAG-66 (CVCL_9918)

[Text version]
Cell line name GLAG-66
Accession CVCL_9918
Resource Identification Initiative To cite this cell line use: GLAG-66 (RRID:CVCL_9918)
Comments Population: Caucasian; Italian.
Derived from site: Metastatic; Thyroid gland; UBERON=UBERON_0002046.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from child cell line K1).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu542Lys (c.1624G>A); ClinVar=VCV000031944; Zygosity=Heterozygous (from child cell line K1).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Heterozygous; Note=In promoter (from child cell line K1).
Disease Thyroid gland papillary carcinoma (NCIt: C4035)
Differentiated thyroid carcinoma (ORDO: Orphanet_146)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_2537 (K1)CVCL_6308 (K2 [Human thyroid carcinoma])CVCL_1322 (K5)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line

PubMed=8330267; DOI=10.1016/0165-4608(93)90163-G
Antonini P., Linares G., Gaillard N., Venuat A.-M., Schlumberger M., Travagli J.-P., Caillou B., Berger R., Parmentier C.
Cytogenetic characterization of a new human papillary thyroid carcinoma permanent cell line (GLAG-66).
Cancer Genet. Cytogenet. 67:117-122(1993)

PubMed=19087340; DOI=10.1186/1471-2407-8-371
Ribeiro F.R., Meireles A.M., Rocha A.S., Teixeira M.R.
Conventional and molecular cytogenetics of human non-medullary thyroid carcinoma: characterization of eight cell line models and review of the literature on clinical samples.
BMC Cancer 8:371.1-371.11(2008)

Cell line databases/resources cancercelllines; CVCL_9918
Anatomy/cell type resources BTO; BTO:0006406
Encyclopedic resources Wikidata; Q54835892
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number19