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Cellosaurus UKF-NB-2rDOX100 (CVCL_9909)

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Cell line name UKF-NB-2rDOX100
Synonyms UKF-NB-2 DOXO
Accession CVCL_9909
Resource Identification Initiative To cite this cell line use: UKF-NB-2rDOX100 (RRID:CVCL_9909)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Doubling time: 21 hours (PubMed=12532417).
Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9902 (UKF-NB-2)
Category Cancer cell line
Web pages Provider; RCCL; -; https://www.wass-michaelislab.org/rccl.php
Publications

PubMed=12532417; DOI=10.1002/ijc.10917
Rouslan Kotchetkov, Jaroslaw Cinatl, Roman A. Blaheta, Jens-Uwe Vogel, Jana Karaskova, Jeremy Andrew Squire, Pablo Hernaiz Driever, Thomas Klingebiel, Jindrich Cinatl Jr.;
Development of resistance to vincristine and doxorubicin in neuroblastoma alters malignant properties and induces additional karyotype changes: a preclinical model.
Int. J. Cancer 104:36-43(2003)

PubMed=16151587
Jiri B. Bedrnicek, Ales Vicha, Marie Jarosova, Milena Holzerova, Jindrich Cinatl Jr., Martin Michaelis, Jaroslaw Cinatl, Tomas Eckschlager;
Characterization of drug-resistant neuroblastoma cell lines by comparative genomic hybridization.
Neoplasma 52:415-419(2005)

PubMed=17505515; DOI=10.1038/sj.bjc.6603777; PMCID=PMC2359931
Roman A. Blaheta, Martin Michaelis, Iyad Natsheh, Christoph Hasenberg, Eva Weich, Borna Relja, Dietger Jonas, Hans-Wilhelm Doerr, Jindrich Cinatl Jr.;
Valproic acid inhibits adhesion of vincristine- and cisplatin-resistant neuroblastoma tumour cells to endothelium.
Br. J. Cancer 96:1699-1706(2007)

Cross-references
Encyclopedic resources Wikidata; Q54990294
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number16