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Cellosaurus Okajima (CVCL_9815)

[Text version]
Cell line name Okajima
Synonyms OKAJIMA
Accession CVCL_9815
Resource Identification Initiative To cite this cell line use: Okajima (RRID:CVCL_9815)
Comments Population: Japanese.
Doubling time: 36-40 hours (PubMed=3962675); 36-38 hours (CelloPub=CLPUB00584).
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Misspelling: Okajama; IARC_TP53=999.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
HLA typing Source: PubMed=26589293
Class I
HLA-AA*11:01,31:01
HLA-BB*15:27,51:01
HLA-CC*03:03,15:02
Class II
HLA-DRDRB1*11:16,14:121
Disease Gastric undifferentiated carcinoma (NCIt: C5476)
Undifferentiated carcinoma of stomach (ORDO: Orphanet_423786)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 38Y
Category Cancer cell line
STR profile Source(s): PubMed=25877200

Markers:
AmelogeninX
CSF1PO11,12
D2S133817,24
D3S135817,18
D5S81811
D7S8208,12
D8S117914,15
D13S3179
D16S5399,11
D18S5115,18
D19S43314.2
D21S1129,30
FGA19,25
Penta D9,12
Penta E17,21
TH018
TPOX8
vWA14

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Publications

CLPUB00584
Teiichi Motoyama, Haruto Hojo, Toshimitsu Suzuki, Shoichi Oboshi;
Evaluation of the regrowth assay method as an in vitro drug sensitivity test and its application to cultured human gastric cancer cell lines.
Acta Med. Biol. 27:49-63(1979)

PubMed=6862145; DOI=10.20772/cancersci1959.74.2_240
Seiji Naito, Sadami Inoue, Mitsuru Kinjo, Kenzo Tanaka;
Thromboplastic and fibrinolytic activities of cultured human gastric cancer cell lines.
Gann 74:240-247(1983)

PubMed=3962675; DOI=10.1111/j.1440-1827.1986.tb01461.x
Teiichi Motoyama, Haruto Hojo, Hidenobu Watanabe;
Comparison of seven cell lines derived from human gastric carcinomas.
Acta Pathol. Jpn. 36:65-83(1986)

PubMed=1933850
Yukishige Yamada, Teruhiko Yoshida, Kenshi Hayashi, Takao Sekiya, Jun Yokota, Setsuo Hirohashi, Katsunori Nakatani, Hiroshige Nakano, Takashi Sugimura, Masaaki Terada;
p53 gene mutations in gastric cancer metastases and in gastric cancer cell lines derived from metastases.
Cancer Res. 51:5800-5805(1991)

PubMed=15723654; DOI=10.1111/j.1349-7006.2005.00016.x; PMCID=PMC11160020
Hisashi Takada, Issei Imoto, Hitoshi Tsuda, Itaru Sonoda, Takashi Ichikura, Hidetaka Mochizuki, Takeshi Okanoue, Johji Inazawa;
Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization.
Cancer Sci. 96:100-110(2005)

PubMed=17505008; DOI=10.1158/1078-0432.CCR-06-2743
Masayuki Takeda, Tokuzo Arao, Hideyuki Yokote, Teruo Komatsu, Kazuyoshi Yanagihara, Hiroki Sasaki, Yasuhide Yamada, Tomohide Tamura, Kazuya Fukuoka, Hiroshi Kimura, Nagahiro Saijo, Kazuto Nishio;
AZD2171 shows potent antitumor activity against gastric cancer over-expressing fibroblast growth factor receptor 2/keratinocyte growth factor receptor.
Clin. Cancer Res. 13:3051-3057(2007)

PubMed=24807215; DOI=10.1038/ncomms4830; PMCID=PMC4024760
Jin-Feng Liu, Mark L. McCleland, Eric W. Stawiski, Florian Gnad, Oleg Mayba, Peter M. Haverty, Steffen Durinck, Ying-Jiun Chen, Christiaan Klijn, Suchit Jhunjhunwala, Michael Lawrence ...Show all 30 authors... , Han-Bin Liu, Yi-Nan Wan, Vivek S. Chopra, Murat Burat Yaylaoglu, Wen-Lin Yuan, Connie Ha, Houston N. Gilbert, Jens Reeder, Gregoire Pau, Jeremy Stinson, Howard M. Stern, Gerard Manning, Thomas D. Wu, Richard M. Neve, Frederic J. de Sauvage, Zora Modrusan, Somasekar Seshagiri, Ron Firestein, Ze-Min Zhang; Show fewer authors
Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.
Nat. Commun. 5:3830.1-3830.8(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Christiaan Klijn, Steffen Durinck, Eric W. Stawiski, Peter M. Haverty, Zhao-Shi Jiang, Han-Bin Liu, Jeremiah Degenhardt, Oleg Mayba, Florian Gnad, Jin-Feng Liu, Gregoire Pau ...Show all 30 authors... , Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh K. Selvaraj, Ma-Mie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Clifford Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrusan, Richard M. Neve, Frederic J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Ze-Min Zhang; Show fewer authors
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_9815
CGH-DB; 123-1
CGH-DB; 9025-4
Biological sample resources BioSample; SAMN03470905
Chemistry resources PharmacoDB; Okajima_1198_2019
Encyclopedic resources Wikidata; Q54931911
Experimental variables resources EFO; EFO_0006715
Gene expression databases ArrayExpress; E-MTAB-2706
Polymorphism and mutation databases Cosmic; 926117
Cosmic; 1001656
Cosmic; 1518258
Cosmic; 2443795
IARC_TP53; 999
Sequence databases EGA; EGAS00001000610
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number25