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Cellosaurus DKO-3 (CVCL_9799)

[Text version]
Cell line name DKO-3
Synonyms DKO3
Accession CVCL_9799
Resource Identification Initiative To cite this cell line use: DKO-3 (RRID:CVCL_9799)
Comments Population: Caucasian.
Characteristics: In DLD-1 one of the two KRAS alleles has a p.Gly13Asp mutation. This cell line is KO for the mutant allele.
Knockout cell: Method=Homologous recombination; HGNC; 6407; KRAS (Note=1 of 2 alleles).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0248 (DLD-1)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=8465203; DOI=10.1126/science.8465203
Shirasawa S., Furuse M., Yokoyama N., Sasazuki T.
Altered growth of human colon cancer cell lines disrupted at activated Ki-ras.
Science 260:85-88(1993)

Cross-references
Encyclopedic resources Wikidata; Q54831120
Entry history
Entry creation06-Jun-2012
Last entry update30-Jan-2024
Version number10