Cellosaurus cell line STA-ET-2.2 (CVCL

Cellosaurus STA-ET-2.2 (CVCL_9687)

Cross-references
Cell line name	STA-ET-2.2
Synonyms	St. Anna Kinderspital-Ewing Tumor-2.2
Accession	CVCL_9687
Resource Identification Initiative	To cite this cell line use: STA-ET-2.2 (RRID:CVCL_9687)
Comments	From: Children's Cancer Research Institute; Vienna; Austria. Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys277Tyr (c.830G>A); ClinVar=VCV000185722; Zygosity=Unspecified (PubMed=8378080).
Disease	Ewing sarcoma (NCIt: C4817) Ewing sarcoma (ORDO: Orphanet_319)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_9686 ! STA-ET-2.1
Sex of cell	Male
Age at sampling	15Y
Category	Cancer cell line
Publications	PubMed=8378080 Heinrich Kovar, Andreas Auinger, Gunhild Jug, Dave N.T. Aryee, Andreas Zoubek, Mechthild Salzer-Kuntschik, Helmut Gadner; Narrow spectrum of infrequent p53 mutations and absence of MDM2 amplification in Ewing tumours. Oncogene 8:2683-2690(1993) PubMed=9393981; DOI=10.1038/sj.onc.1201397 Heinrich Kovar, Gunhild Jug, Dave N.T. Aryee, Andreas Zoubek, Peter F. Ambros, Bernadette Gruber, Reinhard Windhager, Helmut Gadner; Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors. Oncogene 15:2225-2232(1997)
Cell line databases/resources	cancercelllines; CVCL_9687
Encyclopedic resources	Wikidata; Q54955772
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	15