ID   STA-ET-2.2
AC   CVCL_9687
SY   St. Anna Kinderspital-Ewing Tumor-2.2
DR   cancercelllines; CVCL_9687
DR   Wikidata; Q54955772
RX   PubMed=8378080;
RX   PubMed=9393981;
CC   From: Children's Cancer Research Institute; Vienna; Austria.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys277Tyr (c.830G>A); ClinVar=VCV000185722; Zygosity=Unspecified (PubMed=8378080).
CC   Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C4817; Ewing sarcoma
DI   ORDO; Orphanet_319; Ewing sarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_9686 ! STA-ET-2.1
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 15
//
RX   PubMed=8378080;
RA   Kovar H., Auinger A., Jug G., Aryee D.N.T., Zoubek A.,
RA   Salzer-Kuntschik M., Gadner H.;
RT   "Narrow spectrum of infrequent p53 mutations and absence of MDM2
RT   amplification in Ewing tumours.";
RL   Oncogene 8:2683-2690(1993).
//
RX   PubMed=9393981; DOI=10.1038/sj.onc.1201397;
RA   Kovar H., Jug G., Aryee D.N.T., Zoubek A., Ambros P.F., Gruber B.,
RA   Windhager R., Gadner H.;
RT   "Among genes involved in the RB dependent cell cycle regulatory
RT   cascade, the p16 tumor suppressor gene is frequently lost in the Ewing
RT   family of tumors.";
RL   Oncogene 15:2225-2232(1997).
//