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Cellosaurus SN12C-PM6 (CVCL_9549)

[Text version]
Cell line name SN12C-PM6
Synonyms SN12CPM6; SN12-PM6; SN12PM6; PM6; LM1
Accession CVCL_9549
Resource Identification Initiative To cite this cell line use: SN12C-PM6 (RRID:CVCL_9549)
Comments Population: Caucasian.
Omics: Transcriptomics; Microarray.
Omics: Variations; CNV analysis.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu336Ter (c.1006G>T); Zygosity=Homozygous (from parent cell line).
Disease Renal cell carcinoma (NCIt: C9385)
Renal cell carcinoma (ORDO: Orphanet_217071)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1705 (SN12C)
Children:
CVCL_DG80 (SN12C-PM6-2)
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=2706827; DOI=10.1007/BF01753659
Seiji Naito, Shirley M. Walker, Isaiah Joshua Fidler;
In vivo selection of human renal cell carcinoma cells with high metastatic potential in nude mice.
Clin. Exp. Metastasis 7:381-389(1989)

PubMed=8053494; PMCID=PMC1887407
Rakesh K. Singh, Corazon D. Bucana, Mordechai Gutman, Dominic Fan, Michael R. Wilson, Isaiah Joshua Fidler;
Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells.
Am. J. Pathol. 145:365-374(1994)

PubMed=10987313
Seiji Yano, Hisashi Shinohara, Roy S. Herbst, Hiroki Kuniyasu, Corazon D. Bucana, Lee M. Ellis, Darren W. Davis, David J. McConkey, Isaiah Joshua Fidler;
Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis.
Cancer Res. 60:4959-4967(2000)

PubMed=20952505; DOI=10.1158/0008-5472.CAN-10-2279; PMCID=PMC3281492
Miguel A. Lopez-Lago, Venkata J. Thodima, Asha Guttapalli, Timothy Chan, Adriana Heguy, Ana M. Molina, Victor E. Reuter, Robert J. Motzer, Raju S.K. Chaganti;
Genomic deregulation during metastasis of renal cell carcinoma implements a myofibroblast-like program of gene expression.
Cancer Res. 70:9682-9692(2010)

Cross-references
Cell line collections (Providers) KCLB; 80026
Cell line databases/resources cancercelllines; CVCL_9549
Encyclopedic resources Wikidata; Q54955020
Gene expression databases GEO; GSM374474
GEO; GSM579206
GEO; GSM579401
Polymorphism and mutation databases Progenetix; CVCL_9549
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number19