ID   SN12C-PM6
AC   CVCL_9549
SY   SN12CPM6; SN12-PM6; SN12PM6; PM6; LM1
DR   cancercelllines; CVCL_9549
DR   GEO; GSM374474
DR   GEO; GSM579206
DR   GEO; GSM579401
DR   KCLB; 80026
DR   Progenetix; CVCL_9549
DR   Wikidata; Q54955020
RX   PubMed=2706827;
RX   PubMed=8053494;
RX   PubMed=10987313;
RX   PubMed=20952505;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Glu336Ter (c.1006G>T); Zygosity=Homozygous (from parent cell line).
CC   Omics: CNV analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C9385; Renal cell carcinoma
DI   ORDO; Orphanet_217071; Renal cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1705 ! SN12C
SX   Male
AG   43Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 17
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RX   PubMed=2706827; DOI=10.1007/BF01753659;
RA   Naito S., Walker S.M., Fidler I.J.;
RT   "In vivo selection of human renal cell carcinoma cells with high
RT   metastatic potential in nude mice.";
RL   Clin. Exp. Metastasis 7:381-389(1989).
//
RX   PubMed=8053494;
RA   Singh R.K., Bucana C.D., Gutman M., Fan D., Wilson M.R., Fidler I.J.;
RT   "Organ site-dependent expression of basic fibroblast growth factor in
RT   human renal cell carcinoma cells.";
RL   Am. J. Pathol. 145:365-374(1994).
//
RX   PubMed=10987313;
RA   Yano S., Shinohara H., Herbst R.S., Kuniyasu H., Bucana C.D.,
RA   Ellis L.M., Davis D.W., McConkey D.J., Fidler I.J.;
RT   "Expression of vascular endothelial growth factor is necessary but not
RT   sufficient for production and growth of brain metastasis.";
RL   Cancer Res. 60:4959-4967(2000).
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RX   PubMed=20952505; DOI=10.1158/0008-5472.CAN-10-2279;
RA   Lopez-Lago M.A., Thodima V.J., Guttapalli A., Chan T., Heguy A.,
RA   Molina A.M., Reuter V.E., Motzer R.J., Chaganti R.S.K.;
RT   "Genomic deregulation during metastasis of renal cell carcinoma
RT   implements a myofibroblast-like program of gene expression.";
RL   Cancer Res. 70:9682-9692(2010).
//