| Publications | PubMed=1906341; DOI=10.1002/gcc.2870030111
Thomas W. Glover, Constance K. Stein, Eric Legius, Lone B. Andersen, Anne Brereton, Susan Johnson;
Molecular and cytogenetic analysis of tumors in von Recklinghausen neurofibromatosis.
Genes Chromosomes Cancer 3:62-70(1991) PubMed=1568246; DOI=10.1016/0092-8674(92)90407-4
Jeffrey E. DeClue, Alexander G. Papageorge, Jonathan A. Fletcher, Scott R. Diehl, Nancy Ratner, William C. Vass, Douglas Ronald Lowy;
Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis.
Cell 69:265-273(1992) PubMed=7627966
Ning Yan, Carolyn S. Ricca, Jonathan A. Fletcher, Thomas W. Glover, Bernd R. Seizinger, Veeraswamy Manne;
Farnesyltransferase inhibitors block the neurofibromatosis type I (NF1) malignant phenotype.
Cancer Res. 55:3569-3575(1995) PubMed=9766530; DOI=10.1002/(SICI)1097-4652(199811)177:2<334::AID-JCP15>3.0.CO;2-9
Ali Badache, George H. de Vries;
Neurofibrosarcoma-derived Schwann cells overexpress platelet-derived growth factor (PDGF) receptors and are induced to proliferate by PDGF BB.
J. Cell. Physiol. 177:334-342(1998) PubMed=10791998; DOI=10.1172/JCI7610; PMCID=PMC315438
Jeffrey E. DeClue, Sue C. Heffelfinger, Giovanna Benvenuto, Bo Ling, Shao-Wei Li, Wen Rui, William C. Vass, David Viskochil, Nancy Ratner;
Epidermal growth factor receptor expression in neurofibromatosis type 1-related tumors and NF1 animal models.
J. Clin. Invest. 105:1233-1241(2000) PubMed=16239399; DOI=10.1124/jpet.105.091454
Raymond Richard Mattingly, Janice M. Kraniak, Joshua T. Dilworth, Patricia Mathieu, Beverly Bealmear, James E. Nowak, Joyce A. Benjamins, Michael A. Tainsky, John J. Reiners Jr.;
The mitogen-activated protein kinase/extracellular signal-regulated kinase kinase inhibitor PD184352 (CI-1040) selectively induces apoptosis in malignant schwannoma cell lines.
J. Pharmacol. Exp. Ther. 316:456-465(2006) PubMed=16510576; DOI=10.1158/0008-5472.CAN-05-3330
Shyra J. Miller, Fatima Rangwala, Jon Williams, Peter Ackerman, Sue Kong, Anil G. Jegga, Sergio Kaiser, Bruce J. Aronow, Silke Frahm, Lan Kluwe, Victor-Felix Mautner ...Show all 20 authors... , Meena Upadhyaya, David F. Muir 4th, Margaret R. Wallace, Jussara Hagen, Dawn E. Quelle, Mark A. Watson, Arie Perry, David Hillel Gutmann, Nancy Ratner; Show fewer authors
Large-scale molecular comparison of human Schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues.
Cancer Res. 66:2584-2591(2006) PubMed=18650488; DOI=10.1215/15228517-2008-053; PMCID=PMC2719009
Nikola Holtkamp, Elke Malzer, Jan Zietsch, Ali Fuat Okuducu, Jana Mucha, Christian Mawrin, Victor-Felix Mautner, Hans-Ulrich Schildhaus, Andreas von Deimling;
EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy.
Neuro-oncol. 10:946-957(2008) PubMed=21084276; DOI=10.1158/0008-5472.CAN-10-2799; PMCID=PMC3064267
Gonzalo Lopez, Keila Enitt Torres, Jeffrey Jue-Hui Liu, Belinda Hernandez, Eric D. Young, Roman Belousov, Svetlana V. Bolshakov, Alexander J.F. Lazar, John M. Slopis, Ian E. McCutcheon, David J. McConkey, Dina Chelouche Lev;
Autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors.
Cancer Res. 71:185-196(2011) PubMed=22346343; DOI=10.4137/TOG.S8830; PMCID=PMC3273949
Dao-Chun Sun, Michael A. Tainsky, Ramsi Haddad;
Oncogene mutation survey in MPNST cell lines enhances the dominant role of hyperactive Ras in NF1 associated pro-survival and malignancy.
Transl. Oncogenomics 5:1-7(2012) PubMed=23437333; DOI=10.1371/journal.pone.0057152; PMCID=PMC3578816
David E. Reuss, Jana Mucha, Christian Hagenlocher, Volker Ehemann, Lan Kluwe, Victor-Felix Mautner, Andreas von Deimling;
Sensitivity of malignant peripheral nerve sheath tumor cells to TRAIL is augmented by loss of NF1 through modulation of MYC/MAD and is potentiated by curcumin through induction of ROS.
PLoS ONE 8:e57152.1-e57152.10(2013) PubMed=24726063; DOI=10.1186/1756-9966-33-33; PMCID=PMC4022359
Christian Koelsche, Marcus Renner, Wolfgang Hartmann, Regine Brandt, Burkhard Lehner, Nina Waldburger, Ingo Alldinger, Thomas Schmitt, Gerlinde Egerer, Roland Penzel, Eva Wardelmann ...Show all 14 authors... , Peter Schirmacher, Andreas von Deimling, Gunhild Mechtersheimer; Show fewer authors
TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities.
J. Exp. Clin. Cancer Res. 33:33.1-33.8(2014) PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074; PMCID=PMC4636476
Beverly A. Teicher, Eric C. Polley, Mark W. Kunkel, David Evans, Thomas E. Silvers, Rene M. Delosh, Julie Laudeman, Chad Ogle, Russell Reinhart, Michael Selby, John Connelly ...Show all 14 authors... , Erik Harris, Anne Monks, Joel Morris; Show fewer authors
Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression.
Mol. Cancer Ther. 14:2452-2462(2015) PubMed=28469964; PMCID=PMC5411799
Jian-Man Guo, Michael R. Grovola, Hong Xie, Grace E. Coggins, Patrick Duggan, Rukhsana Hasan, Jia-Le Huang, Danny W. Lin, Claire Song, Gabriela M. Witek, Simon Berritt ...Show all 13 authors... , David C. Schultz, Jeffrey Field; Show fewer authors
Comprehensive pharmacological profiling of neurofibromatosis cell lines.
Am. J. Cancer Res. 7:923-934(2017) PubMed=28556483; DOI=10.1002/1878-0261.12086; PMCID=PMC5579334
Matthias Kolberg, Jarle Bruun, Astrid Murumagi, John Patrick Mpindi, Christian H. Bergsland, Maren Holand, Ina A. Eilertsen, Stine A. Danielsen, Olli-Pekka Kallioniemi, Ragnhild Adelheid Lothe;
Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors.
Mol. Oncol. 11:1156-1171(2017) PubMed=32076030; DOI=10.1038/s41598-020-59789-4; PMCID=PMC7031337
Azadeh Amirnasr, Robert M. Verdijk, Patricia F. van Kuijk, Pinar Kartal, Anne L.M. Vriends, Pim J. French, Martin Eduard van Royen, Walter Taal, Stefan Sleijfer, Erik A.C. Wiemer;
Deregulated microRNAs in neurofibromatosis type 1 derived malignant peripheral nerve sheath tumors.
Sci. Rep. 10:2927.1-2927.14(2020) PubMed=32642732; DOI=10.1093/noajnl/vdz049; PMCID=PMC7317054
Alexander Pemov, Hua Li, William Presley, Margaret R. Wallace, David T. Miller;
Genetics of human malignant peripheral nerve sheath tumors.
Neurooncol. Adv. 2:i50-i61(2020) PubMed=34059954; DOI=10.1007/s00439-021-02296-x
Miriam Magallon-Lorenz, Juana Fernandez-Rodriguez, Ernest Terribas, Edgar Creus-Bachiller, Cleofe Romagosa, Anna Estival, Diana Perez Sidelnikova, Hector Salvador, Alberto Villanueva, Ignacio Blanco, Meritxell Carrio ...Show all 14 authors... , Conxi Lazaro, Eduard Serra, Bernat Gel; Show fewer authors
Chromosomal translocations inactivating CDKN2A support a single path for malignant peripheral nerve sheath tumor initiation.
Hum. Genet. 140:1241-1252(2021) PubMed=36818284; DOI=10.1016/j.isci.2023.106096; PMCID=PMC9929861
Miriam Magallon-Lorenz, Ernest Terribas, Sara Ortega-Bertran, Edgar Creus-Bachiller, Marco Fernandez, Gerard Requena, Inma Rosas, Helena Mazuelas, Itziar Uriarte-Arrazola, Alex Negro, Tereza Lausova ...Show all 28 authors... , Elisabeth Castellanos, Ignacio Blanco, George Henry DeVries, Hiroyuki Kawashima, Eric Legius, Hilde Brems, Victor-Felix Mautner, Lan Kluwe, Nancy Ratner, Margaret R. Wallace, Juana Fernandez-Rodriguez, Conxi Lazaro, Jonathan A. Fletcher, David E. Reuss, Meritxell Carrio, Bernat Gel, Eduard Serra; Show fewer authors
Deep genomic analysis of malignant peripheral nerve sheath tumor cell lines challenges current malignant peripheral nerve sheath tumor diagnosis.
iScience 26:106096.1-106096.22(2023) PubMed=37798904; DOI=10.1002/1878-0261.13534; PMCID=PMC10994238
Edgar Creus-Bachiller, Juana Fernandez-Rodriguez, Miriam Magallon-Lorenz, Sara Ortega-Bertran, Susana Navas-Rutete, Cleofe Romagosa, Tulio M. Silva, Maria Pane Foix, Anna Estival, Diana Perez Sidelnikova, Mireia Morell Ginesta ...Show all 19 authors... , Helena Mazuelas, Meritxell Carrio, Tereza Lausova, David E. Reuss, Bernat Gel, Alberto Villanueva, Eduard Serra, Conxi Lazaro; Show fewer authors
Expanding a precision medicine platform for malignant peripheral nerve sheath tumors: new patient-derived orthotopic xenografts, cell lines and tumor entities.
Mol. Oncol. 18:895-917(2024) |
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