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Cellosaurus SA-4 (CVCL_8910)

[Text version]
Cell line name SA-4
Synonyms SA4; TxS-HuSa1; SA4TXS1
Accession CVCL_8910
Resource Identification Initiative To cite this cell line use: SA-4 (RRID:CVCL_8910)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=1246601; PubMed=4469665; PubMed=20143388). Originally thought to originate from a male patient suffering from a liposarcoma.
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00085.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: SNP array analysis.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

PubMed=4469665; DOI=10.1126/science.184.4141.1093
Nelson-Rees W.A., Flandermeyer R.R., Hawthorne P.K.
Banded marker chromosomes as indicators of intraspecies cellular contamination.
Science 184:1093-1096(1974)

PubMed=1246601; DOI=10.1126/science.1246601
Nelson-Rees W.A., Flandermeyer R.R.
HeLa cultures defined.
Science 191:96-98(1976)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=22911243; DOI=10.1155/2012/148614
Stratford E.W., Castro R., Daffinrud J., Skarn M., Lauvrak S., Munthe E., Myklebost O.
Characterization of liposarcoma cell lines for preclinical and biological studies.
Sarcoma 2012:148614.1-148614.9(2012)

PubMed=26643872; DOI=10.18632/oncotarget.6464
Kanojia D., Nagata Y., Garg M., Lee D.H., Sato A., Yoshida K., Sato Y., Sanada M., Mayakonda A., Bartenhagen C., Klein H.-U., Doan N.B., Said J.W., Mohith S., Gunasekar S., Shiraishi Y., Chiba K., Tanaka H., Miyano S., Myklebost O., Yang H., Dugas M., Meza-Zepeda L.A., Silberman A.W., Forscher C., Tyner J.W., Ogawa S., Koeffler H.P.
Genomic landscape of liposarcoma.
Oncotarget 6:42429-42444(2015)

Cell line collections (Providers) ATCC; CRL-7938 - Discontinued
Biological sample resources BioSample; SAMN03151754
Encyclopedic resources Wikidata; Q54951988
Polymorphism and mutation databases Cosmic; 2800528
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number21