Cellosaurus cell line SA-4 (CVCL

Cellosaurus SA-4 (CVCL_8910)

Cross-references
Cell line name	SA-4
Synonyms	SA4; TxS-HuSa1; SA4TXS1
Accession	CVCL_8910
Resource Identification Initiative	To cite this cell line use: SA-4 (RRID:CVCL_8910)
Comments	Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=1246601; PubMed=4469665; PubMed=20143388). Originally thought to originate from a male patient suffering from a liposarcoma. Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982). Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00085. Population: African American. Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Omics: SNP array analysis. Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease	Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0030 (HeLa)
Sex of cell	Female
Age at sampling	30Y6M
Category	Cancer cell line
Web pages	https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications	PubMed=4469665; DOI=10.1126/science.184.4141.1093 Nelson-Rees W.A., Flandermeyer R.R., Hawthorne P.K. Banded marker chromosomes as indicators of intraspecies cellular contamination. Science 184:1093-1096(1974) PubMed=1246601; DOI=10.1126/science.1246601 Nelson-Rees W.A., Flandermeyer R.R. HeLa cultures defined. Science 191:96-98(1976) PubMed=20143388; DOI=10.1002/ijc.25242 Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I. Check your cultures! A list of cross-contaminated or misidentified cell lines. Int. J. Cancer 127:1-8(2010) PubMed=22911243; DOI=10.1155/2012/148614 Stratford E.W., Castro R., Daffinrud J., Skarn M., Lauvrak S., Munthe E., Myklebost O. Characterization of liposarcoma cell lines for preclinical and biological studies. Sarcoma 2012:148614.1-148614.9(2012) PubMed=26643872; DOI=10.18632/oncotarget.6464 Kanojia D., Nagata Y., Garg M., Lee D.H., Sato A., Yoshida K., Sato Y., Sanada M., Mayakonda A., Bartenhagen C., Klein H.-U., Doan N.B., Said J.W., Mohith S., Gunasekar S., Shiraishi Y., Chiba K., Tanaka H., Miyano S., Myklebost O., Yang H., Dugas M., Meza-Zepeda L.A., Silberman A.W., Forscher C., Tyner J.W., Ogawa S., Koeffler H.P. Genomic landscape of liposarcoma. Oncotarget 6:42429-42444(2015)
Cell line collections (Providers)	ATCC; CRL-7938 - Discontinued
Biological sample resources	BioSample; SAMN03151754
Encyclopedic resources	Wikidata; Q54951988
Polymorphism and mutation databases	Cosmic; 2800528
Entry history
Entry creation	06-Jun-2012
Last entry update	05-Oct-2023
Version number	21