ID   SA-4
AC   CVCL_8910
SY   SA4; TxS-HuSa1; SA4TXS1
DR   ATCC; CRL-7938
DR   BioSample; SAMN03151754
DR   Cosmic; 2800528
DR   Wikidata; Q54951988
RX   PubMed=1246601;
RX   PubMed=4469665;
RX   PubMed=20143388;
RX   PubMed=22911243;
RX   PubMed=26643872;
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=1246601; PubMed=4469665; PubMed=20143388). Originally thought to originate from a male patient suffering from a liposarcoma.
CC   Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00085.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Omics: SNP array analysis.
CC   Discontinued: ATCC; CRL-7938; true.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 02-05-24; Version: 22
RX   PubMed=1246601; DOI=10.1126/science.1246601;
RA   Nelson-Rees W.A., Flandermeyer R.R.;
RT   "HeLa cultures defined.";
RL   Science 191:96-98(1976).
RX   PubMed=4469665; DOI=10.1126/science.184.4141.1093;
RA   Nelson-Rees W.A., Flandermeyer R.R., Hawthorne P.K.;
RT   "Banded marker chromosomes as indicators of intraspecies cellular
RT   contamination.";
RL   Science 184:1093-1096(1974).
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
RX   PubMed=22911243; DOI=10.1155/2012/148614;
RA   Stratford E.W., Castro R., Daffinrud J., Skarn M., Lauvrak S.,
RA   Munthe E., Myklebost O.;
RT   "Characterization of liposarcoma cell lines for preclinical and
RT   biological studies.";
RL   Sarcoma 2012:148614.1-148614.9(2012).
RX   PubMed=26643872; DOI=10.18632/oncotarget.6464;
RA   Kanojia D., Nagata Y., Garg M., Lee D.H., Sato A., Yoshida K.,
RA   Sato Y., Sanada M., Mayakonda A., Bartenhagen C., Klein H.-U.,
RA   Doan N.B., Said J.W., Mohith S., Gunasekar S., Shiraishi Y., Chiba K.,
RA   Tanaka H., Miyano S., Myklebost O., Yang H., Dugas M.,
RA   Meza-Zepeda L.A., Silberman A.W., Forscher C., Tyner J.W., Ogawa S.,
RA   Koeffler H.P.;
RT   "Genomic landscape of liposarcoma.";
RL   Oncotarget 6:42429-42444(2015).