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Cellosaurus FLYA13 (CVCL_8870)

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Cell line name FLYA13
Synonyms FLY-A13; FLY-AF-13
Accession CVCL_8870
Resource Identification Initiative To cite this cell line use: FLYA13 (RRID:CVCL_8870)
Comments Group: Retrovirus packaging cell line.
Population: Caucasian.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Fibrosarcoma (NCIt: C3043)
Fibrosarcoma (ORDO: Orphanet_2030)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0317 (HT-1080)
Children:
CVCL_EG37 (FLYA-JET)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
STR profile Source(s): ECACC=95091901

Markers:
AmelogeninX,Y
CSF1PO12
D5S81811,13
D7S8209,10
D13S31712,14
D16S5399,12
TH016
TPOX8
vWA14,19

Run an STR similarity search on this cell line
Publications

PubMed=7494248; DOI=10.1128/JVI.69.12.7430-7436.1995; PMCID=PMC189680
Francois-Loic Cosset, Yasuhiro Takeuchi, Jean-Luc Battini, Robin Anthony Weiss, Mary Katherine Levinge Collins;
High-titer packaging cells producing recombinant retroviruses resistant to human serum.
J. Virol. 69:7430-7436(1995)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) CancerTools; 151655
ECACC; 95091901 - Discontinued
Ximbio; 151655
Cell line databases/resources CLO; CLO_0003368
CLDB; cl1376
cancercelllines; CVCL_8870
LINCS_LDP; LCL-1437
Encyclopedic resources Wikidata; Q54835019
Gene expression databases GEO; GSM827429
Polymorphism and mutation databases Progenetix; CVCL_8870
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number31