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Cellosaurus SJNB-1 (CVCL_8812)

[Text version]
Cell line name SJNB-1
Synonyms SJ-NB-1; SJ-NB1; SJNB1; SJNB-1(EB); NB1
Accession CVCL_8812
Resource Identification Initiative To cite this cell line use: SJNB-1 (RRID:CVCL_8812)
Comments Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 2Y6M
Category Cancer cell line
Publications

PubMed=8516298; DOI=10.1073/pnas.90.12.5539; PMCID=PMC46756
Maureen Riordan Johnson, Alfred Thomas Look, Jeffrey E. DeClue, Marcus B. Valentine, Douglas Ronald Lowy;
Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras.
Proc. Natl. Acad. Sci. U.S.A. 90:5539-5543(1993)

PubMed=7838528
Ngan Ching Cheng, Nadine Van Roy, Alvin Chan, Mabel Beitsma, Andries Westerveld, Frank Speleman, Rogier Versteeg;
Deletion mapping in neuroblastoma cell lines suggests two distinct tumor suppressor genes in the 1p35-36 region, only one of which is associated with N-myc amplification.
Oncogene 10:291-297(1995)

DOI=10.1007/0-306-46872-7_2
Carol Jeanne Thiele;
Neuroblastoma.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.21-53; Kluwer Academic Publishers; New York; USA (1999)

PubMed=10935473; DOI=10.1038/sj.neo.7900010; PMCID=PMC1716055
Xiao-Tang Kong, Virginia A. Valentine, Susan T. Rowe, Marcus B. Valentine, Susan T. Ragsdale, Bart G. Jones, Deborah A. Wilkinson, Garrett M. Brodeur, Susan Lerner Cohn, Alfred Thomas Look;
Lack of homozygously inactivated p73 in single-copy MYCN primary neuroblastomas and neuroblastoma cell lines.
Neoplasia 1:80-89(1999)

PubMed=10933967; DOI=10.1006/mthe.2000.0064
Cynthia A. Pawlik, Rekha V. Iyengar, Erik J. Krull, Stephen E. Mason, Ruchi Khanna, Linda C. Harris, Philip M. Potter, Mary K. Danks, Sylvie M. Guichard;
Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated overexpression of a rabbit carboxylesterase to sensitize neuroblastoma cells to CPT-11.
Mol. Ther. 1:457-463(2000)

PubMed=11550280; DOI=10.1002/gcc.1174
Nadine Van Roy, Heidi Van Limbergen, Jo Vandesompele, Mireille Van Gele, Bruce Poppe, Helen R. Salwen, Genevieve Laureys, Nunes Manoel, Anne De Paepe, Frank Speleman;
Combined M-FISH and CGH analysis allows comprehensive description of genetic alterations in neuroblastoma cell lines.
Genes Chromosomes Cancer 32:126-135(2001)

PubMed=18923524; DOI=10.1038/nature07399
Yu-Yan Chen, Junko Takita, Young Lim Choi, Motohiro Kato, Miki Ohira, Masashi Sanada, Li-Li Wang, Manabu Soda, Akira Kikuchi, Takashi Igarashi, Akira Nakagawara ...Show all 14 authors... , Yasuhide Hayashi, Hiroyuki Mano, Seishi Ogawa; Show fewer authors
Oncogenic mutations of ALK kinase in neuroblastoma.
Nature 455:971-974(2008)

PubMed=20655465; DOI=10.1016/j.cell.2010.06.004; PMCID=PMC2913027
Michael Holzel, Si-Dong Huang, Jan Koster, Ingrid Ora, Arjan Lakeman, Huib Nicolaas Caron, Wouter Nijkamp, Jing Xie, Tom Callens, Shahab Asgharzadeh, Robert C. Seeger ...Show all 14 authors... , Ludwine M. Messiaen, Rogier Versteeg, Rene Bernards; Show fewer authors
NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome.
Cell 142:218-229(2010)

PubMed=22213050; DOI=10.1002/ijc.27415; PMCID=PMC3757132
Joanna E. Gawecka, Dirk Geerts, Jan Koster, Maisel J. Caliva, Florian J. Sulzmaier, John Opoku-Ansah, Randal K. Wada, Andre S. Bachmann, Joe W. Ramos;
PEA15 impairs cell migration and correlates with clinical features predicting good prognosis in neuroblastoma.
Int. J. Cancer 131:1556-1568(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8812
Anatomy/cell type resources BTO; BTO_0006053
Chemistry resources ChEMBL-Cells; CHEMBL3308822
ChEMBL-Targets; CHEMBL2366284
PubChem_Cell_line; CVCL_8812
Encyclopedic resources Wikidata; Q54953553
Gene expression databases GEO; GSM314019
GEO; GSM333806
GEO; GSM692870
Polymorphism and mutation databases Cosmic; 947712
Cosmic; 1037331
Cosmic; 1099128
Cosmic; 1109106
Cosmic; 1153792
Cosmic; 1518073
Cosmic; 1526641
Cosmic; 2131598
Cosmic; 2239468
IARC_TP53; 23605
Progenetix; CVCL_8812
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number20