Cellosaurus logo
expasy logo

Cellosaurus HKMUS (CVCL_8776)

[Text version]
Cell line name HKMUS
Accession CVCL_8776
Resource Identification Initiative To cite this cell line use: HKMUS (RRID:CVCL_8776)
Comments Problematic cell line: Contaminated. Shown to be a SKG-II-SF derivative (PubMed=20143388). Originally thought to originate from a 50 year old female patient with an uterine large cell non-keratinizing squamous cell carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00311.
Population: Japanese.
Doubling time: 37 hours (PubMed=10457904).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Sequence variations
  • Mutation; HGNC; HGNC:7773; NF2; Simple; p.Ser87Ter (c.260C>A); Zygosity=Unspecified (from parent cell line).
Disease Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_8159 (SKG-II-SF)
Children:
CVCL_8230 (HKMUS-SF)
Sex of cell Female
Age at sampling 50Y
Category Cancer cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=2429643; DOI=10.1111/j.1447-0756.1986.tb00192.x
Isamu Ishiwata, Chieko Ishiwata, Shiro Nozawa, Hiroshi Ishikawa;
CA125 production by gynecologic tumors in vitro and its modulation induced by dibutyl cyclic adenosine monophosphate.
Asia Oceania J. Obstet. Gynaecol. 12:285-290(1986)

PubMed=2448191; DOI=10.1016/0090-8258(88)90151-5
Isamu Ishiwata, Chieko Ishiwata, Masayuki Soma, Isao Ono, Takenori Nakaguchi, Hiroshi Ishikawa;
Tumor angiogenic activity of gynecologic tumor cell lines on the chorioallantoic membrane.
Gynecol. Oncol. 29:87-93(1988)

PubMed=1698374
Isamu Ishiwata, Chieko Ishiwata, Masayuki Soma, Isao Ono, Takenori Nakaguchi, Shiro Nozawa, Hiroshi Ishikawa;
Differences between cell lines of uterine cervical glassy cell carcinoma and large cell nonkeratinizing squamous cell carcinoma.
Anal. Quant. Cytol. Histol. 12:290-298(1990)

PubMed=9436037
Masayuki Soma, Isamu Ishiwata, Chieko Ishiwata, Takenori Nakaguchi, Isao Ono, Kazushige Kiguchi, Hisashi Hashimoto, Toshiaki Tachibana, Hiroshi Ishikawa, Shiro Nozawa;
Tissue reconstruction of gynecologic tumor cells in the rotation culture system.
Hum. Cell 10:175-181(1997)

PubMed=10457904
Isamu Ishiwata, Tadashi Sudo, Kazushige Kiguchi, Hiroshi Ishikawa;
Tumor angiogenesis factors produced by cancer cells.
Hum. Cell 12:37-46(1999)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM01930
Biological sample resources BioSample; SAMN03151914
Encyclopedic resources Wikidata; Q54889776
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number28