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Cellosaurus HTMMT (CVCL_8721)

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Cell line name HTMMT
Accession CVCL_8721
Resource Identification Initiative To cite this cell line use: HTMMT (RRID:CVCL_8721)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: 72 hours (Note=At 20th passage), 70 hours (Note=At 40th passage), 60 hours (Note=At 50th passage) (PubMed=15859158).
Derived from site: In situ; Uterus; UBERON=UBERON_0000995.
Sequence variations
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Arg130Gly (c.388C>G); ClinVar=VCV000375958; Zygosity=Unspecified (DepMap=ACH-002046).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Ter404Leuext*8 (c.1211G>T); Zygosity=Unspecified (DepMap=ACH-002046).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (DepMap=ACH-002046).
Disease Uterine carcinosarcoma (NCIt: C42700)
Carcinosarcoma of the corpus uteri (ORDO: Orphanet_213610)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line
STR profile Source(s): RCB=RCB0660

Markers:
AmelogeninX
CSF1PO12
D5S81811,12
D7S82010
D13S31710,13
D16S53910,11
TH018,9
TPOX8,11
vWA19

Run an STR similarity search on this cell line
Publications

PubMed=9573483
Isamu Ishiwata, Yuko Tokieda, Chieko Ishiwata, Natsumi Okane, Megumi Iguchi, Kahei Sato, Hiroshi Ishikawa;
Effects of feeder cells (human cancer cell lines) on the development of mouse embryos by co-culture.
Hum. Cell 10:237-246(1997)

PubMed=15859158; DOI=10.1111/j.1749-0774.2004.tb00029.x
Isamu Ishiwata, Chieko Ishiwata, Masayuki Soma, Megumi Iguchi, Kazushige Kiguchi, Tomoharu Tamagawa, Iwao Ishiwata, Hiroshi Ishikawa;
Histogenesis of carcinosarcoma and establishment of leiomyosarcoma cell line (HTMMT) derived from human uterine carcinosarcoma.
Hum. Cell 17:131-137(2004)

Cross-references
Cell line collections (Providers) RCB; RCB0660
Cell line databases/resources CLO; CLO_0050882
cancercelllines; CVCL_8721
DepMap; ACH-002046
Biological sample resources BioSample; SAMN03472266
Encyclopedic resources Wikidata; Q54896669
Gene expression databases FANTOM5_SSTAR; 10689-109F5
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number25