ID   HTMMT
AC   CVCL_8721
DR   CLO; CLO_0050882
DR   BioSample; SAMN03472266
DR   cancercelllines; CVCL_8721
DR   DepMap; ACH-002046
DR   RCB; RCB0660
DR   Wikidata; Q54896669
RX   PubMed=9573483;
RX   PubMed=15859158;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Japanese.
CC   Doubling time: 72 hours (Note=At 20th passage), 70 hours (Note=At 40th passage), 60 hours (Note=At 50th passage) (PubMed=15859158).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Arg130Gly (c.388C>G); ClinVar=VCV000375958; Zygosity=Unspecified (DepMap=ACH-002046).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Ter404Leuext*8 (c.1211G>T); Zygosity=Unspecified (DepMap=ACH-002046).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (DepMap=ACH-002046).
CC   Derived from site: In situ; Uterus; UBERON=UBERON_0000995.
ST   Source(s): RCB=RCB0660
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 10,13
ST   D16S539: 10,11
ST   D5S818: 11,12
ST   D7S820: 10
ST   TH01: 8,9
ST   TPOX: 8,11
ST   vWA: 19
DI   NCIt; C42700; Uterine carcinosarcoma
DI   ORDO; Orphanet_213610; Carcinosarcoma of the corpus uteri
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   66Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 23
//
RX   PubMed=9573483;
RA   Ishiwata I., Tokieda Y., Ishiwata C., Okane N., Iguchi M., Sato K.,
RA   Ishikawa H.;
RT   "Effects of feeder cells (human cancer cell lines) on the development
RT   of mouse embryos by co-culture.";
RL   Hum. Cell 10:237-246(1997).
//
RX   PubMed=15859158; DOI=10.1111/j.1749-0774.2004.tb00029.x;
RA   Ishiwata I., Ishiwata C., Soma M., Iguchi M., Kiguchi K., Tamagawa T.,
RA   Ishiwata I., Ishikawa H.;
RT   "Histogenesis of carcinosarcoma and establishment of leiomyosarcoma
RT   cell line (HTMMT) derived from human uterine carcinosarcoma.";
RL   Hum. Cell 17:131-137(2004).
//