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Cellosaurus HS-PSS (CVCL_8717)

[Text version]
Cell line name HS-PSS
Synonyms Hs-PSS; HSPSS
Accession CVCL_8717
Resource Identification Initiative To cite this cell line use: HS-PSS (RRID:CVCL_8717)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Karyotypic information: Average ploidy of 1.82 (PubMed=36818284).
Omics: Genomics; Whole exome sequencing.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Sequence variations
Disease Malignant peripheral nerve sheath tumor (NCIt: C3798)
Malignant peripheral nerve sheath tumor (ORDO: Orphanet_3148)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=28556483; PubMed=33707600; PubMed=36818284; RCB=RCB2362

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133819
D3S135816
D5S8189,11
D7S82010,12
D8S117914,15 (PubMed=28556483; PubMed=36818284)
14,15,19 (PubMed=33707600)
D13S3178,10
D16S53910
D18S5114,15
D19S43310.2,12,13 (PubMed=33707600)
13 (PubMed=28556483; PubMed=36818284)
D21S1128,32
FGA22
TH016,9
TPOX8
vWA14,15

Run an STR similarity search on this cell line
Publications

PubMed=28556483; DOI=10.1002/1878-0261.12086; PMCID=PMC5579334
Kolberg M., Bruun J., Murumagi A., Mpindi J.P., Bergsland C.H., Holand M., Eilertsen I.A., Danielsen S.A., Kallioniemi O.-P., Lothe R.A.
Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors.
Mol. Oncol. 11:1156-1171(2017)

PubMed=33707600; DOI=10.1038/s41598-021-85055-2; PMCID=PMC7952412
Longo J.F., Brosius S.N., Znoyko I., Alers V.A., Jenkins D.P., Wilson R.C., Carroll A.J. 3rd, Wolff D.J., Roth K.A., Carroll S.L.
Establishment and genomic characterization of a sporadic malignant peripheral nerve sheath tumor cell line.
Sci. Rep. 11:5690.1-5690.19(2021)

PubMed=34059954; DOI=10.1007/s00439-021-02296-x
Magallon-Lorenz M., Fernandez-Rodriguez J., Terribas E., Creus-Bachiller E., Romagosa C., Estival A., Perez Sidelnikova D., Salvador H., Villanueva A., Blanco I., Carrio M., Lazaro C., Serra E., Gel B.
Chromosomal translocations inactivating CDKN2A support a single path for malignant peripheral nerve sheath tumor initiation.
Hum. Genet. 140:1241-1252(2021)

PubMed=36818284; DOI=10.1016/j.isci.2023.106096; PMCID=PMC9929861
Magallon-Lorenz M., Terribas E., Ortega-Bertran S., Creus-Bachiller E., Fernandez M., Requena G., Rosas I., Mazuelas H., Uriarte-Arrazola I., Negro A., Lausova T., Castellanos E., Blanco I., DeVries G.H., Kawashima H., Legius E., Brems H., Mautner V.-F., Kluwe L., Ratner N., Wallace M.R., Fernandez-Rodriguez J., Lazaro C., Fletcher J.A., Reuss D.E., Carrio M., Gel B., Serra E.
Deep genomic analysis of malignant peripheral nerve sheath tumor cell lines challenges current malignant peripheral nerve sheath tumor diagnosis.
iScience 26:106096.1-106096.22(2023)

Cross-references
Cell line collections (Providers) RCB; RCB2362
Cell line databases/resources CLO; CLO_0051534
DepMap; ACH-002065
Biological sample resources BioSample; SAMN03471914
Encyclopedic resources Wikidata; Q54896288
Gene expression databases FANTOM5_SSTAR; 10442-106F1
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number17