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Cellosaurus HS-PSS (CVCL_8717)

[Text version]
Cell line name HS-PSS
Synonyms Hs-PSS; HSPSS
Accession CVCL_8717
Resource Identification Initiative To cite this cell line use: HS-PSS (RRID:CVCL_8717)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Karyotypic information: Average ploidy of 1.82 (PubMed=36818284).
Omics: Genomics; Whole exome sequencing.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Sequence variations
Disease Malignant peripheral nerve sheath tumor (NCIt: C3798)
Malignant peripheral nerve sheath tumor (ORDO: Orphanet_3148)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=28556483; PubMed=33707600; PubMed=36818284; RCB=RCB2362

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133819
D3S135816
D5S8189,11
D7S82010,12
D8S117914,15 (PubMed=28556483; PubMed=36818284)
14,15,19 (PubMed=33707600)
D13S3178,10
D16S53910
D18S5114,15
D19S43310.2,12,13 (PubMed=33707600)
13 (PubMed=28556483; PubMed=36818284)
D21S1128,32
FGA22
TH016,9
TPOX8
vWA14,15

Run an STR similarity search on this cell line
Publications

PubMed=28556483; DOI=10.1002/1878-0261.12086; PMCID=PMC5579334
Matthias Kolberg, Jarle Bruun, Astrid Murumagi, John Patrick Mpindi, Christian H. Bergsland, Maren Holand, Ina A. Eilertsen, Stine A. Danielsen, Olli-Pekka Kallioniemi, Ragnhild Adelheid Lothe;
Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors.
Mol. Oncol. 11:1156-1171(2017)

PubMed=33707600; DOI=10.1038/s41598-021-85055-2; PMCID=PMC7952412
Jody Fromm Longo, Stephanie N. Brosius, Iya Znoyko, Victoria A. Alers, Dorea Pleasant Jenkins, Robert C. Wilson, Andrew J. Carroll 3rd, Daynna J. Wolff, Kevin A. Roth, Steven Lewis Carroll;
Establishment and genomic characterization of a sporadic malignant peripheral nerve sheath tumor cell line.
Sci. Rep. 11:5690.1-5690.19(2021)

PubMed=34059954; DOI=10.1007/s00439-021-02296-x
Miriam Magallon-Lorenz, Juana Fernandez-Rodriguez, Ernest Terribas, Edgar Creus-Bachiller, Cleofe Romagosa, Anna Estival, Diana Perez Sidelnikova, Hector Salvador, Alberto Villanueva, Ignacio Blanco, Meritxell Carrio ...Show all 14 authors... , Conxi Lazaro, Eduard Serra, Bernat Gel; Show fewer authors
Chromosomal translocations inactivating CDKN2A support a single path for malignant peripheral nerve sheath tumor initiation.
Hum. Genet. 140:1241-1252(2021)

PubMed=36818284; DOI=10.1016/j.isci.2023.106096; PMCID=PMC9929861
Miriam Magallon-Lorenz, Ernest Terribas, Sara Ortega-Bertran, Edgar Creus-Bachiller, Marco Fernandez, Gerard Requena, Inma Rosas, Helena Mazuelas, Itziar Uriarte-Arrazola, Alex Negro, Tereza Lausova ...Show all 28 authors... , Elisabeth Castellanos, Ignacio Blanco, George Henry DeVries, Hiroyuki Kawashima, Eric Legius, Hilde Brems, Victor-Felix Mautner, Lan Kluwe, Nancy Ratner, Margaret R. Wallace, Juana Fernandez-Rodriguez, Conxi Lazaro, Jonathan A. Fletcher, David E. Reuss, Meritxell Carrio, Bernat Gel, Eduard Serra; Show fewer authors
Deep genomic analysis of malignant peripheral nerve sheath tumor cell lines challenges current malignant peripheral nerve sheath tumor diagnosis.
iScience 26:106096.1-106096.22(2023)

Cross-references
Cell line collections (Providers) RCB; RCB2362
Cell line databases/resources CLO; CLO_0051534
DepMap; ACH-002065
Biological sample resources BioSample; SAMN03471914
Encyclopedic resources Wikidata; Q54896288
Gene expression databases FANTOM5_SSTAR; 10442-106F1
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number17