ID   HS-PSS
AC   CVCL_8717
SY   Hs-PSS; HSPSS
DR   CLO; CLO_0051534
DR   BioSample; SAMN03471914
DR   DepMap; ACH-002065
DR   FANTOM5_SSTAR; 10442-106F1
DR   RCB; RCB2362
DR   Wikidata; Q54896288
RX   PubMed=28556483;
RX   PubMed=33707600;
RX   PubMed=34059954;
RX   PubMed=36818284;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Japanese.
CC   Karyotypic information: Average ploidy of 1.82 (PubMed=36818284).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=34059954).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (PubMed=34059954).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
ST   Source(s): PubMed=28556483; PubMed=33707600; PubMed=36818284; RCB=RCB2362
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 8,10
ST   D16S539: 10
ST   D18S51: 14,15
ST   D19S433: 10.2,12,13 (PubMed=33707600)
ST   D19S433: 13 (PubMed=28556483; PubMed=36818284)
ST   D21S11: 28,32
ST   D2S1338: 19
ST   D3S1358: 16
ST   D5S818: 9,11
ST   D7S820: 10,12
ST   D8S1179: 14,15 (PubMed=28556483; PubMed=36818284)
ST   D8S1179: 14,15,19 (PubMed=33707600)
ST   FGA: 22
ST   TH01: 6,9
ST   TPOX: 8
ST   vWA: 14,15
DI   NCIt; C3798; Malignant peripheral nerve sheath tumor
DI   ORDO; Orphanet_3148; Malignant peripheral nerve sheath tumor
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 17
//
RX   PubMed=28556483; DOI=10.1002/1878-0261.12086; PMCID=PMC5579334;
RA   Kolberg M., Bruun J., Murumagi A., Mpindi J.P., Bergsland C.H.,
RA   Holand M., Eilertsen I.A., Danielsen S.A., Kallioniemi O.-P.,
RA   Lothe R.A.;
RT   "Drug sensitivity and resistance testing identifies PLK1 inhibitors
RT   and gemcitabine as potent drugs for malignant peripheral nerve sheath
RT   tumors.";
RL   Mol. Oncol. 11:1156-1171(2017).
//
RX   PubMed=33707600; DOI=10.1038/s41598-021-85055-2; PMCID=PMC7952412;
RA   Longo J.F., Brosius S.N., Znoyko I., Alers V.A., Jenkins D.P.,
RA   Wilson R.C., Carroll A.J. 3rd, Wolff D.J., Roth K.A., Carroll S.L.;
RT   "Establishment and genomic characterization of a sporadic malignant
RT   peripheral nerve sheath tumor cell line.";
RL   Sci. Rep. 11:5690.1-5690.19(2021).
//
RX   PubMed=34059954; DOI=10.1007/s00439-021-02296-x;
RA   Magallon-Lorenz M., Fernandez-Rodriguez J., Terribas E.,
RA   Creus-Bachiller E., Romagosa C., Estival A., Perez Sidelnikova D.,
RA   Salvador H., Villanueva A., Blanco I., Carrio M., Lazaro C., Serra E.,
RA   Gel B.;
RT   "Chromosomal translocations inactivating CDKN2A support a single path
RT   for malignant peripheral nerve sheath tumor initiation.";
RL   Hum. Genet. 140:1241-1252(2021).
//
RX   PubMed=36818284; DOI=10.1016/j.isci.2023.106096; PMCID=PMC9929861;
RA   Magallon-Lorenz M., Terribas E., Ortega-Bertran S., Creus-Bachiller E.,
RA   Fernandez M., Requena G., Rosas I., Mazuelas H., Uriarte-Arrazola I.,
RA   Negro A., Lausova T., Castellanos E., Blanco I., DeVries G.H.,
RA   Kawashima H., Legius E., Brems H., Mautner V.-F., Kluwe L., Ratner N.,
RA   Wallace M.R., Fernandez-Rodriguez J., Lazaro C., Fletcher J.A.,
RA   Reuss D.E., Carrio M., Gel B., Serra E.;
RT   "Deep genomic analysis of malignant peripheral nerve sheath tumor cell
RT   lines challenges current malignant peripheral nerve sheath tumor
RT   diagnosis.";
RL   iScience 26:106096.1-106096.22(2023).
//