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Cellosaurus HP100-1 (CVCL_8710)

[Text version]
Cell line name HP100-1
Synonyms HL60 HP100-1
Accession CVCL_8710
Resource Identification Initiative To cite this cell line use: HP100-1 (RRID:CVCL_8710)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:16240; Hydrogen peroxide.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
STR profile Source(s): RCB=RCB0769


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PubMed=2796382; DOI=10.1016/0145-2126(89)90088-X
Kasugai I., Yamada M.
Adaptation of human leukemia HL-60 cells to hydrogen peroxide as oxidative stress.
Leuk. Res. 13:757-762(1989)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

Cell line collections (Providers) RCB; RCB0769
Cell line databases/resources CLO; CLO_0050987
cancercelllines; CVCL_8710
Encyclopedic resources Wikidata; Q54890202
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number27