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Cellosaurus HP100-1 (CVCL_8710)

[Text version]
Cell line name HP100-1
Synonyms HL60 HP100-1
Accession CVCL_8710
Resource Identification Initiative To cite this cell line use: HP100-1 (RRID:CVCL_8710)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_16240; Hydrogen peroxide.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia with maturation (NCIt: C7961)
Acute myeloblastic leukemia with maturation (ORDO: Orphanet_98834)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
STR profile Source(s): RCB=RCB0769

Markers:
AmelogeninX
CSF1PO13,14
D5S81812
D7S82011,12
D13S3178,11
D16S53911
TH018
TPOX8,11
vWA16

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Publications

PubMed=2796382; DOI=10.1016/0145-2126(89)90088-X
Isao Kasugai, Michiyuki Yamada;
Adaptation of human leukemia HL-60 cells to hydrogen peroxide as oxidative stress.
Leuk. Res. 13:757-762(1989)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Li-Qun Jia, Motonobu Osada, Chikashi Ishioka, Makio Gamo, Shuntaro Ikawa, Takao Suzuki, Hideki Shimodaira, Tomohito Niitani, Toshio Kudo, Mitoshi Akiyama, Narimiti Kimura ...Show all 18 authors... , Mitsuyoshi Matsuo, Hiroshi Mizusawa, Noriho Tanaka, Hideki Koyama, Masayoshi Namba, Ryunosuke Kanamaru, Toshio Kuroki; Show fewer authors
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

Cross-references
Cell line collections (Providers) RCB; RCB0769
Cell line databases/resources CLO; CLO_0050987
cancercelllines; CVCL_8710
Encyclopedic resources Wikidata; Q54890202
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number29