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Cellosaurus CaVe (CVCL_8444)

[Text version]
Cell line name CaVe
Synonyms Cancer Ventriculi
Accession CVCL_8444
Resource Identification Initiative To cite this cell line use: CaVe (RRID:CVCL_8444)
Comments Group: Space-flown cell line (cellonaut).
Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=58478; PubMed=6451928; PubMed=20143388). Originally thought to originate from a gastric carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00036.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Anecdotal: Have been flown in space on Zond-5 to study growth in microgravity (PubMed=11942358).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
CVCL_WN72 (CaVe K-10V)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

PubMed=14071827; DOI=10.1093/jnci/31.5.1173
Dobrynin Y.V.
Establishment and characteristics of cell strains from some epithelial tumors of human origin.
J. Natl. Cancer Inst. 31:1173-1195(1963)

Zhukov-Verezhnikov N.N., Volkov M.N., Maisky I.N., Rybakov N.I., Guberniev M.A., Podoplelov I.I., Kulagin A.N., Aniskin E.D., Rybakova K.D., Sharyi N.I., Voronkova I.P., Saxonov P.P., Kopyev V.Y., Antipov V.V., Kozlov V.A., Parfyonov G.P., Orlovsky V.I.
Experiments with micro-organisms and human cell cultures in the Zond 5 and Zond 7 flights.
Life Sci. Space Res. 9:99-103(1971)

Kulagina O.E., Muzurenko N.P., Pogosiants E.E.
Karyotypic analysis of human cell lines (CaVe and HeLa) by the method of differential staining of chromosomes.
Vopr. Virusol. 20:677-681(1975)

PubMed=6451928; DOI=10.1126/science.6451928
Nelson-Rees W.A., Daniels D.W., Flandermeyer R.R.
Cross-contamination of cells in culture.
Science 212:446-452(1981)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Biological sample resources BioSample; SAMN03151671
Encyclopedic resources Wikidata; Q54808631
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number23