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Cellosaurus CaVe (CVCL_8444)

[Text version]
Cell line name CaVe
Synonyms Cancer Ventriculi
Accession CVCL_8444
Resource Identification Initiative To cite this cell line use: CaVe (RRID:CVCL_8444)
Comments Group: Space-flown cell line (cellonaut).
Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=58478; PubMed=6451928; PubMed=20143388). Originally thought to originate from a gastric carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00036.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Anecdotal: Have been flown in space on Zond-5 to study growth in microgravity (PubMed=11942358).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Children:
CVCL_WN72 (CaVe K-10V)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=14071827; DOI=10.1093/jnci/31.5.1173
Yaroslav V. Dobrynin;
Establishment and characteristics of cell strains from some epithelial tumors of human origin.
J. Natl. Cancer Inst. 31:1173-1195(1963)

PubMed=11942358
Nikolai Nikolaevich Zhukov-Verezhnikov, M.N. Volkov, I.N. Maisky, N.I. Rybakov, M.A. Guberniev, I.I. Podoplelov, A.N. Kulagin, E.D. Aniskin, K.D. Rybakova, N.I. Sharyi, I.P. Voronkova ...Show all 17 authors... , P.P. Saxonov, V.Y. Kopyev, V.V. Antipov, V.A. Kozlov, G.P. Parfyonov, V.I. Orlovsky; Show fewer authors
Experiments with micro-organisms and human cell cultures in the Zond 5 and Zond 7 flights.
Life Sci. Space Res. 9:99-103(1971)

PubMed=58478
Olga E. Kulagina, N.P. Muzurenko, E.E. Pogosiants;
Karyotypic analysis of human cell lines (CaVe and HeLa) by the method of differential staining of chromosomes.
Vopr. Virusol. 20:677-681(1975)

PubMed=6451928; DOI=10.1126/science.6451928
Walter Anthony Nelson-Rees, David W. Daniels, Robert R. Flandermeyer;
Cross-contamination of cells in culture.
Science 212:446-452(1981)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Biological sample resources BioSample; SAMN03151671
Encyclopedic resources Wikidata; Q54808631
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number25