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Cellosaurus PEAZ-1 (CVCL_8437)

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Cell line name PEAZ-1
Accession CVCL_8437
Resource Identification Initiative To cite this cell line use: PEAZ-1 (RRID:CVCL_8437)
Comments Problematic cell line: Contaminated. Shown to be a HT-1080 derivative (PubMed=20143388; CelloPub=CLPUB00698). Originally thought to originate from a prostate carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00257.
Population: Caucasian.
Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Fibrosarcoma (NCIt: C3043)
Fibrosarcoma (ORDO: Orphanet_2030)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0317 (HT-1080)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
STR profile Source(s): CelloPub=CLPUB00698

Markers:
AmelogeninX,Y
D3S135816
D5S81811,13
D7S8209,10
D8S117913,14
D13S31712
D18S5112,18
D21S1128,30
FGA22,25
vWA14,19

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=11433418; DOI=10.1002/pros.1084
Martin Schmelz, Anne Elizabeth Cress, Jose Barrera, Kathleen M. McDaniel, Tracy L. Davis, Laura Fuchs, Bruce L. Dalkin, Raymond B. Nagle;
PEAZ-1: a new human prostate neoplastic epithelial cell line.
Prostate 48:79-92(2001)

CLPUB00698
Adrie van Bokhoven;
Models for prostate cancer. Molecular characterization and critical appraisal of human prostate carcinoma cell lines.
Thesis PhD (2004); Katholieke Universiteit Nijmegen; Nijmegen; Netherlands

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8437
Cell_Model_Passport; SIDM00830
Biological sample resources BioSample; SAMN03151782
Encyclopedic resources Wikidata; Q54946897
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number31