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Cellosaurus HAC-2 (CVCL_8354)

[Text version]
Cell line name HAC-2
Synonyms HAC 2; Hac2
Accession CVCL_8354
Resource Identification Initiative To cite this cell line use: HAC-2 (RRID:CVCL_8354)
Comments Part of: MD Anderson Cell Lines Project.
Population: Japanese.
Doubling time: 46.8 hours (CelloPub=CLPUB00045).
Omics: Proteomics; Expression; Reverse-phase protein array.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
Disease Ovarian clear cell adenocarcinoma (NCIt: C40078)
Clear cell adenocarcinoma of the ovary (ORDO: Orphanet_398971)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 52Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1359; JCRB=JCRB1539

Markers:
AmelogeninX
CSF1PO12
D5S81812,13
D7S8209,11
D13S3178,9
D16S53910,11
TH017
TPOX11
vWA14,16

Run an STR similarity search on this cell line
Web pages Info; MCLP; -; https://tcpaportal.org/mclp/
Publications

CLPUB00045
Masato Nishida, Hirokazu Iwasaki;
Establishment of a human ovarian clear cell carcinoma cell line (HAC-2 cells) in vitro.
Hum. Cell 1:345-346(1988)

PubMed=8980248; DOI=10.1002/(SICI)1097-0215(19961220)69:6<466::AID-IJC8>3.0.CO;2-2
Yoshihito Ichikawa, Sadao Yoshida, Yumi Koyama, Misako Hirai, Tomoyoshi Ishikawa, Masato Nishida, Hajime Tsunoda, Takeshi Kubo, Masanao Miwa, Kazuhiko Uchida;
Inactivation of p16/CDKN2 and p15/MTS2 genes in different histological types and clinical stages of primary ovarian tumors.
Int. J. Cancer 69:466-470(1996)

PubMed=25846456; DOI=10.3892/ijo.2015.2951
Masataka Takenaka, Motonobu Saito, Reika Iwakawa, Nozomu Yanaihara, Misato Saito, Mamoru Kato, Hitoshi Ichikawa, Tatsuhiro Shibata, Jun Yokota, Aikou Okamoto, Takashi Kohno;
Profiling of actionable gene alterations in ovarian cancer by targeted deep sequencing.
Int. J. Oncol. 46:2389-2398(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections (Providers) JCRB; JCRB1359
JCRB; JCRB1539
JCRB; NIHS0567 - Discontinued
Cell line databases/resources cancercelllines; CVCL_8354
Encyclopedic resources Wikidata; Q54872301
Polymorphism and mutation databases Cosmic; 877480
Cosmic; 931363
Cosmic; 945375
Cosmic; 1152560
Cosmic; 2582795
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number24