Cellosaurus cell line Ger (CVCL

Cellosaurus Ger (CVCL_8353)

Cross-references
Cell line name	Ger
Synonyms	GER
Accession	CVCL_8353
Resource Identification Initiative	To cite this cell line use: Ger (RRID:CVCL_8353)
Comments	Doubling time: 36 hours (Note=At 11th passage) (PubMed=435363).
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=11787853). Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (PubMed=11787853). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=11787853). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val272Leu (c.814G>T); ClinVar=VCV000012358; Zygosity=Unspecified (PubMed=11787853).
Disease	Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	56Y
Category	Cancer cell line
Publications	PubMed=435363; DOI=10.1038/bjc.1979.24; PMCID=PMC2009856 Anne G. Grant, Delojan Duke, John Hermon-Taylor; Establishment and characterization of primary human pancreatic carcinoma in continuous cell culture and in nude mice. Br. J. Cancer 39:143-151(1979) PubMed=11787853; DOI=10.1007/s004280100474 Patrick S. Moore, Bence Sipos, Simonetta Orlandini, Claudio Sorio, Francisco X. Real, Nicholas Robert Lemoine, Thomas M. Gress, Claudio Bassi, Gunter Kloppel, Holger Kalthoff, Hendrik Ungefroren ...Show all 13 authors... , Johannes-Matthias Lohr, Aldo Scarpa; Show fewer authors Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4. Virchows Arch. 439:798-802(2001)
Cell line databases/resources	cancercelllines; CVCL_8353
Anatomy/cell type resources	BTO; BTO_0002865
Encyclopedic resources	Wikidata; Q54835727
Polymorphism and mutation databases	Cosmic; 710856 IARC_TP53; 16740
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	17