ID   Ger
AC   CVCL_8353
SY   GER
DR   BTO; BTO_0002865
DR   cancercelllines; CVCL_8353
DR   Cosmic; 710856
DR   IARC_TP53; 16740
DR   Wikidata; Q54835727
RX   PubMed=435363;
RX   PubMed=11787853;
CC   Doubling time: 36 hours (Note=At 11th passage) (PubMed=435363).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=11787853).
CC   Sequence variation: Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (PubMed=11787853).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=11787853).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val272Leu (c.814G>T); ClinVar=VCV000012358; Zygosity=Unspecified (PubMed=11787853).
DI   NCIt; C8294; Pancreatic adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   56Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 17
//
RX   PubMed=435363; DOI=10.1038/bjc.1979.24; PMCID=PMC2009856;
RA   Grant A.G., Duke D., Hermon-Taylor J.;
RT   "Establishment and characterization of primary human pancreatic
RT   carcinoma in continuous cell culture and in nude mice.";
RL   Br. J. Cancer 39:143-151(1979).
//
RX   PubMed=11787853; DOI=10.1007/s004280100474;
RA   Moore P.S., Sipos B., Orlandini S., Sorio C., Real F.X., Lemoine N.R.,
RA   Gress T.M., Bassi C., Kloppel G., Kalthoff H., Ungefroren H.,
RA   Lohr J.-M., Scarpa A.;
RT   "Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras,
RT   p53, p16 and DPC4/Smad4.";
RL   Virchows Arch. 439:798-802(2001).
//