Cellosaurus cell line ED(27) (CVCL

Cellosaurus ED(27) (CVCL_8345)

Cross-references
Cell line name	ED(27)
Synonyms	ED27
Accession	CVCL_8345
Resource Identification Initiative	To cite this cell line use: ED(27) (RRID:CVCL_8345)
Comments	Problematic cell line: Contaminated. Shown to be a WISH derivative (PubMed=11869090; PubMed=20143388). Originally thought to originate from a chorionic villus sample from a 35 year old female donor. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00191. Population: African American. Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease	Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1909 (WISH)
Sex of cell	Female
Age at sampling	30Y6M
Category	Cancer cell line
Web pages	Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications	PubMed=1415390; DOI=10.1016/S0002-9378(12)80036-6 Eleanor M. Diss, Steven G. Gabbe, Jay W. Moore, Douglas A. Kniss; Study of thromboxane and prostacyclin metabolism in an in vitro model of first-trimester human trophoblast. Am. J. Obstet. Gynecol. 167:1046-1052(1992) PubMed=11869090; DOI=10.1053/plac.2001.0749 Douglas A. Kniss, Y. Xie, Y. Li, S. Kumar, Elizabeth Ane Linton, Paul Cohen, Patty Fan-Havard, Christopher W.G. Redman, Ian L. Sargent; ED(27) trophoblast-like cells isolated from first-trimester chorionic villi are genetically identical to HeLa cells yet exhibit a distinct phenotype. Placenta 23:32-43(2002) PubMed=20143388; DOI=10.1002/ijc.25242 Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney; Check your cultures! A list of cross-contaminated or misidentified cell lines. Int. J. Cancer 127:1-8(2010)
Biological sample resources	BioSample; SAMN03151688
Encyclopedic resources	Wikidata; Q54831952
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	22