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Cellosaurus MA-160 (CVCL_8261)

[Text version]
Cell line name MA-160
Synonyms MA 160; MA160; Microbiological Associates-160
Accession CVCL_8261
Resource Identification Initiative To cite this cell line use: MA-160 (RRID:CVCL_8261)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=66218; PubMed=93571; PubMed=1246601; PubMed=4469665; PubMed=6451928; PubMed=20143388). Originally thought to originate from a benign prostatic hyperplasia biopsy from Monroe Vincent one of the authors of the original paper.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00026.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

PubMed=4319198; DOI=10.1126/science.170.3957.540
Fraley E.E., Ecker S., Vincent M.M.
Spontaneous in vitro neoplastic transformation of adult human prostatic epithelium.
Science 170:540-542(1970)

PubMed=4469665; DOI=10.1126/science.184.4141.1093
Nelson-Rees W.A., Flandermeyer R.R., Hawthorne P.K.
Banded marker chromosomes as indicators of intraspecies cellular contamination.
Science 184:1093-1096(1974)

Biedler J.L.
Chromosome abnormalities in human tumor cells in culture.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.359-394; Springer; New York (1975)

PubMed=1246601; DOI=10.1126/science.1246601
Nelson-Rees W.A., Flandermeyer R.R.
HeLa cultures defined.
Science 191:96-98(1976)

Webber M.M., Horan P.K., Bouldin T.R.
Present status of MA-160 cell line. Prostatic epithelium or HeLa cells.
Invest. Urol. 14:335-343(1977)

Pontes J.E., Choe B., Rose N., Pierce J.M. Jr.
Immunochemical identification of prostatic epithelial cells in culture.
Invest. Urol. 16:483-485(1979)

PubMed=93571; DOI=10.1007/BF02618148
Pontes J.E., Pierce J.M. Jr., Choe B.-K., Rose N.R.
MA 160 and EB33 cell lines: HeLa cell contaminants, hybrids or prostatic epithelial cells?
In Vitro 15:469-472(1979)

PubMed=535908; DOI=10.1007/BF02619151
Nelson-Rees W.A.
Prostatic acid phosphatase in cell lines MA 160, EB33 and HeLa cells.
In Vitro 15:935-935(1979)

PubMed=6451928; DOI=10.1126/science.6451928
Nelson-Rees W.A., Daniels D.W., Flandermeyer R.R.
Cross-contamination of cells in culture.
Science 212:446-452(1981)

Gold M.
A conspiracy of cells. One woman's immortal legacy and the medical scandal it caused.
(In) ISBN 9780887060991; pp.1-171; State University of New York Press; Albany (1986)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Biological sample resources BioSample; SAMN03151741
Encyclopedic resources Wikidata; Q54903695
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number22