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Cellosaurus HCV-29 (CVCL_8228)

[Text version]
Cell line name HCV-29
Synonyms HCV.29; HCV 29; HCV29
Accession CVCL_8228
Resource Identification Initiative To cite this cell line use: HCV-29 (RRID:CVCL_8228)
Comments Caution: HCV-29 is said to be a non-malignant bladder epithelial cell line. But due to the fact that it is immortal and contains AKT and BRAF mutations we consider it to be a bladder carcinoma cell line.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_8451 (Hu1734)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
STR profile Source(s): PubMed=11416159

Markers:
AmelogeninX,Y
D8S117913,16
D18S5113,14
D21S1128,29
FGA22
TH016,8
vWA19,21

Run an STR similarity search on this cell line
Publications

PubMed=6244232
Richard D. Williams;
Human urologic cancer cell lines.
Invest. Urol. 17:359-363(1980)

PubMed=3708594
John R.W. Masters, Peter J. Hepburn, Lawrence Walker, Wilma J. Highman, Ludwik K. Trejdosiewicz, Susan Povey, Mohamed Parkar, Bridget T. Hill, Peter N. Riddle, Leonard Maurice Franks;
Tissue culture model of transitional cell carcinoma: characterization of twenty-two human urothelial cell lines.
Cancer Res. 46:3630-3636(1986)

PubMed=3800330
Maria Debiec-Rychter, Britta Christensen, Jorgen Kieler, Ching Y. Wang;
Chromosomal characterization and isoenzyme pattern of non-malignant and malignant human urothelial cell lines.
Anticancer Res. 6:1237-1244(1986)

PubMed=7905254
Britta Christensen, Claus Hansen, Jorgen Kieler, Jacqueline Schmidt;
Identity of non-malignant human urothelial cell lines classified as transformation grade I (TGrI) and II (TGrII).
Anticancer Res. 13:2187-2191(1993)

PubMed=8900435; DOI=10.1002/(SICI)1097-0215(19961009)68:2<239::AID-IJC17>3.0.CO;2-5
Arkadiusz Grzegorz Klopocki, Anna Krop-Watorek, Danuta Dus, Maciej Ugorski;
Adhesion of human uroepithelial cells to E-selectin: possible involvement of sialosyl LewisA-ganglioside.
Int. J. Cancer 68:239-244(1996)

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
John R.W. Masters, Jim A. Thomson, Bernadette Daly-Burns, Yvonne A. Reid, Wilhelm Gerhard Dirks, Phil Packer, Lorraine H. Toji, Tadao Ohno, Hideyuki Tanabe, Colin Francis Arlett, Lloyd R. Kelland ...Show all 16 authors... , Maureen Harrison, Arvind K. Virmani, Timothy H. Ward, Karen L. Ayres, Paul G. Debenham; Show fewer authors
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=15846775; DOI=10.1002/gcc.20166
Sarah V. Williams, Jacqui Adams, Jane Coulter, Brenda M. Summersgill, Janet M. Shipley, Margaret A. Knowles;
Assessment by M-FISH of karyotypic complexity and cytogenetic evolution in bladder cancer in vitro.
Genes Chromosomes Cancer 43:315-328(2005)

PubMed=23401075; DOI=10.1002/path.4176
Ya-Nan Guo, Yvonne Chekaluk, Jian-Ming Zhang, Jin-Yan Du, Nathanael S. Gray, Chin-Lee Wu, David Joseph Kwiatkowski;
TSC1 involvement in bladder cancer: diverse effects and therapeutic implications.
J. Pathol. 230:17-27(2013)

PubMed=24035680; DOI=10.1016/j.eururo.2013.08.057
Carolyn D. Hurst, Fiona M. Platt, Margaret A. Knowles;
Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urine.
Eur. Urol. 65:367-369(2014)

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Tahlita C.M. Zuiverloon, Florus C. de Jong, James C. Costello, Dan Theodorescu;
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

PubMed=30193179; DOI=10.1016/j.jmbbm.2018.08.036
Joanna Raczkowska, Szymon Prauzner-Bechcicki;
Discrimination between HCV29 and T24 by controlled proliferation of cells co-cultured on substrates with different elasticity.
J. Mech. Behav. Biomed. Mater. 88:217-222(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8228
Encyclopedic resources Wikidata; Q54882078
Polymorphism and mutation databases Cosmic; 925834
Cosmic; 1286002
Cosmic; 1927313
Cosmic; 2212692
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number20