| Cell line name |
BLIN-1 |
| Synonyms |
Blin-1; Blin1; B-lineage 1 |
| Accession |
CVCL_8173 |
| Resource Identification Initiative |
To cite this cell line use: BLIN-1 (RRID:CVCL_8173) |
| Comments |
Problematic cell line: Contaminated. Shown to be a NALM-6 derivative (PubMed=12592342; PubMed=20143388). Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00170. Population: Caucasian. Omics: Transcriptomics; RNAseq. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. |
| Sequence variations |
- Gene fusion; HGNC; HGNC:50800; DUX4 + HGNC; HGNC:5477; IGH; Name(s)=IGH-DUX4; Note=The translocation occurs in the silenced IGH allele (from parent cell line).
- Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Arg1068Ter (c.3202C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Ala146Thr (c.436G>A); ClinVar=VCV002900866; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9864; RARA; Simple; p.Gln45Ter (c.133C>T); ClinVar=VCV000393019; Zygosity=Heterozygous (from parent cell line).
|
| Disease |
Adult B acute lymphoblastic leukemia (NCIt: C9143) Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860) |
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
| Hierarchy |
Parent: CVCL_0092 (NALM-6) Children:
|
| Sex of cell |
Male |
| Age at sampling |
19Y |
| Category |
Cancer cell line |
| Web pages |
Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx |
| Publications | PubMed=2642502; DOI=10.4049/jimmunol.142.1.110 Bernhard Wormann, Janet M. Anderson, James A. Liberty, Kazimiera Gajl-Peczalska, Richard D. Brunning, Teresa L. Silberman, Diane C. Arthur, Tucker W. LeBien; Establishment of a leukemic cell model for studying human pre-B to B cell differentiation. J. Immunol. 142:110-117(1989) PubMed=7919343; DOI=10.1182/blood.V84.7.2253.2253 Nathalie Renard, Valerie Duvert, Jacques Banchereau, Sem Saeland; Interleukin-13 inhibits the proliferation of normal and leukemic human B-cell precursors. Blood 84:2253-2260(1994) DOI=10.1016/B978-0-12-221970-2.50457-5 Hans Gunther Drexler; The leukemia-lymphoma cell line factsbook. (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001) PubMed=12592342; DOI=10.1038/sj.leu.2402799 Hans Gunther Drexler, Wilhelm Gerhard Dirks, Yoshinobu Matsuo, Roderick A.F. MacLeod; False leukemia-lymphoma cell lines: an update on over 500 cell lines. Leukemia 17:416-426(2003) PubMed=20143388; DOI=10.1002/ijc.25242 Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney; Check your cultures! A list of cross-contaminated or misidentified cell lines. Int. J. Cancer 127:1-8(2010) |
| Cross-references |
| Cell line databases/resources |
cancercelllines; CVCL_8173
|
| Biological sample resources |
BioSample; SAMN03151850
|
| Encyclopedic resources |
Wikidata; Q54797358
|
| Gene expression databases |
GEO; GSM3145571
GEO; GSM3145692
|
| Polymorphism and mutation databases |
Cosmic; 1070705
|
| Entry history |
| Entry creation | 04-Apr-2012 |
| Last entry update | 27-Nov-2025 |
| Version number | 34 |
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