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Cellosaurus HN-2 (CVCL_8125)

[Text version]
Cell line name HN-2
Synonyms HN2; LICR-LON-HN2; LICR (LON) HN2; LICR(Lond)-HN 2; LICR-HN2
Accession CVCL_8125
Resource Identification Initiative To cite this cell line use: HN-2 (RRID:CVCL_8125)
Comments Doubling time: 48 hours (PubMed=7195729).
Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_LI54 (LICR-HN2 R10.3)
Sex of cell Male
Age at sampling 49Y
Category Cancer cell line
Publications

PubMed=7195729; DOI=10.1038/bjc.1981.115; PMCID=PMC2010719
Dorothy M. Easty, Gerald C. Easty, Richard Lawrance Carter, Paul Monaghan, Leslie J. Butler;
Ten human carcinoma cell lines derived from squamous carcinomas of the head and neck.
Br. J. Cancer 43:772-785(1981)

PubMed=6387708; DOI=10.1073/pnas.81.21.6632; PMCID=PMC391984
Gaby E. Pfyffer, Gisela Haemmerli, Claus W. Heizmann;
Calcium-binding proteins in human carcinoma cell lines.
Proc. Natl. Acad. Sci. U.S.A. 81:6632-6636(1984)

PubMed=2427339; DOI=10.1016/0277-5379(86)90158-6
Dorothy M. Easty, Gerald C. Easty, Antonio Baici, Richard Lawrance Carter, Stewart Anthony Cederholm-Williams, Heidi Felix, Barry Austin Gusterson, Gisela Haemmerli, Ingrid Helen Hauser-Urfer, Claus W. Heizmann, Marc M. Mareel ...Show all 13 authors... , B. Stehrenberger, Peter Strauli; Show fewer authors
Biological studies of ten human squamous carcinoma cell lines: an overview.
Eur. J. Cancer Clin. Oncol. 22:617-634(1986)

DOI=10.1016/B978-0-12-333530-2.50007-1
Thomas E. Carey;
Head and neck tumor cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.79-120; Academic Press; New York; USA (1994)

PubMed=26032726; DOI=10.1186/s13104-015-1197-6; PMCID=PMC4467624
Carolien Boeckx, Jolien Van den Bossche, Ines De Pauw, Marc Peeters, Filip Lardon, Marc Baay, An Wouters;
The hypoxic tumor microenvironment and drug resistance against EGFR inhibitors: preclinical study in cetuximab-sensitive head and neck squamous cell carcinoma cell lines.
BMC Res. Notes 8:203.1-203.6(2015)

PubMed=26269754; PMCID=PMC4529614
Carolien Boeckx, Lina Blockx, Ken Op de Beeck, Ridha Limame, Guy Van Camp, Marc Peeters, Jan B. Vermorken, Pol Specenier, An Wouters, Marc Baay, Filip Lardon;
Establishment and characterization of cetuximab resistant head and neck squamous cell carcinoma cell lines: focus on the contribution of the AP-1 transcription factor.
Am. J. Cancer Res. 5:1921-1938(2015)

Cross-references
Encyclopedic resources Wikidata; Q54889990
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number16