ID   HN-2
AC   CVCL_8125
SY   HN2; LICR-LON-HN2; LICR (LON) HN2; LICR(Lond)-HN 2; LICR-HN2
DR   Wikidata; Q54889990
RX   DOI=10.1016/B978-0-12-333530-2.50007-1;
RX   PubMed=2427339;
RX   PubMed=6387708;
RX   PubMed=7195729;
RX   PubMed=26032726;
RX   PubMed=26269754;
CC   Doubling time: 48 hours (PubMed=7195729).
CC   Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
DI   NCIt; C4044; Laryngeal squamous cell carcinoma
DI   ORDO; Orphanet_494550; Squamous cell carcinoma of the larynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   49Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 16
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RX   DOI=10.1016/B978-0-12-333530-2.50007-1;
RA   Carey T.E.;
RT   "Head and neck tumor cell lines.";
RL   (In book chapter) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.79-120; Academic Press; New York; USA (1994).
//
RX   PubMed=2427339; DOI=10.1016/0277-5379(86)90158-6;
RA   Easty D.M., Easty G.C., Baici A., Carter R.L.,
RA   Cederholm-Williams S.A., Felix H., Gusterson B.A., Haemmerli G.,
RA   Hauser-Urfer I.H., Heizmann C.W., Mareel M.M., Stehrenberger B.,
RA   Strauli P.;
RT   "Biological studies of ten human squamous carcinoma cell lines: an
RT   overview.";
RL   Eur. J. Cancer Clin. Oncol. 22:617-634(1986).
//
RX   PubMed=6387708; DOI=10.1073/pnas.81.21.6632; PMCID=PMC391984;
RA   Pfyffer G.E., Haemmerli G., Heizmann C.W.;
RT   "Calcium-binding proteins in human carcinoma cell lines.";
RL   Proc. Natl. Acad. Sci. U.S.A. 81:6632-6636(1984).
//
RX   PubMed=7195729; DOI=10.1038/bjc.1981.115; PMCID=PMC2010719;
RA   Easty D.M., Easty G.C., Carter R.L., Monaghan P., Butler L.J.;
RT   "Ten human carcinoma cell lines derived from squamous carcinomas of
RT   the head and neck.";
RL   Br. J. Cancer 43:772-785(1981).
//
RX   PubMed=26032726; DOI=10.1186/s13104-015-1197-6; PMCID=PMC4467624;
RA   Boeckx C., Van den Bossche J., De Pauw I., Peeters M., Lardon F.,
RA   Baay M., Wouters A.;
RT   "The hypoxic tumor microenvironment and drug resistance against EGFR
RT   inhibitors: preclinical study in cetuximab-sensitive head and neck
RT   squamous cell carcinoma cell lines.";
RL   BMC Res. Notes 8:203.1-203.6(2015).
//
RX   PubMed=26269754; PMCID=PMC4529614;
RA   Boeckx C., Blockx L., Op de Beeck K., Limame R., Van Camp G.,
RA   Peeters M., Vermorken J.B., Specenier P., Wouters A., Baay M.,
RA   Lardon F.;
RT   "Establishment and characterization of cetuximab resistant head and
RT   neck squamous cell carcinoma cell lines: focus on the contribution of
RT   the AP-1 transcription factor.";
RL   Am. J. Cancer Res. 5:1921-1938(2015).
//