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Cellosaurus M20 [Human mesothelioma] (CVCL_8103)

[Text version]
Cell line name M20 [Human mesothelioma]
Accession CVCL_8103
Resource Identification Initiative To cite this cell line use: M20 [Human mesothelioma] (RRID:CVCL_8103)
Comments Transformant: ChEBI; CHEBI:46661; Asbestos.
Donor information: Established after the patient had undergone chemotherapy (PubMed=2323006).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=1568228).
Disease Pleural epithelioid mesothelioma (NCIt: C45662)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_8102 ! M14K
CVCL_U345 ! M14P
Sex of cell Male
Age at sampling 43-61Y
Category Cancer cell line
Publications

PubMed=2323006; DOI=10.1093/carcin/11.4.673
Pelin-Enlund K., Husgafvel-Pursiainen K., Tammilehto L., Klockars M., Jantunen K., Gerwin B.I., Harris C.C., Tuomi T., Vanhala E., Mattson K., Linnainmaa K.
Asbestos-related malignant mesothelioma: growth, cytology, tumorigenicity and consistent chromosome findings in cell lines from five patients.
Carcinogenesis 11:673-681(1990)

PubMed=1568228
Metcalf R.A., Welsh J.A., Bennett W.P., Seddon M.B., Lehman T.A., Pelin-Enlund K., Linnainmaa K., Tammilehto L., Mattson K., Gerwin B.I., Harris C.C.
p53 and Kirsten-ras mutations in human mesothelioma cell lines.
Cancer Res. 52:2610-2615(1992)

Cross-references
Encyclopedic resources Wikidata; Q54903516
Polymorphism and mutation databases Cosmic; 733828
IARC_TP53; 23631
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number14