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Cellosaurus T3M-10 (CVCL_8067)

[Text version]
Cell line name T3M-10
Synonyms T3M10
Accession CVCL_8067
Resource Identification Initiative To cite this cell line use: T3M-10 (RRID:CVCL_8067)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: NCI RAS program mutant KRAS cell line panel.
Population: Japanese.
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (DepMap=ACH-000813).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ala161Thr (c.481G>A); ClinVar=VCV000161518; Zygosity=Homozygous (DepMap=ACH-000813).
HLA typing Source: PubMed=26589293
Class I
Class II
Genome ancestry Source: PubMed=30894373

Origin% genome
Native American0
East Asian, North84.13
East Asian, South11.41
South Asian0
European, North0
European, South2.71
Disease Lung large cell carcinoma (NCIt: C4450)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
STR profile Source(s): RCB=RCB1020


Run an STR similarity search on this cell line

PubMed=6088016; DOI=10.1002/1097-0142(19840915)54:6<1024::AID-CNCR2820540616>3.0.CO;2-1
Okabe T., Fujisawa M., Kudo H., Honma H., Ohsawa N., Takaku F.
Establishment of a human colony-stimulating-factor-producing cell line from an undifferentiated large cell carcinoma of the lung.
Cancer 54:1024-1029(1984)

Okabe T., Kaizu T., Fujisawa M., Watanabe J., Kojima K., Yamashita T., Takaku F.
Monoclonal antibodies to surface antigens of small cell carcinoma of the lung.
Cancer Res. 44:5273-5278(1984)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cell line collections (Providers) RCB; RCB1020
Cell line databases/resources CLO; CLO_0050071
cancercelllines; CVCL_8067
Cell_Model_Passport; SIDM01764
DepMap; ACH-000813
Biological sample resources BioSample; SAMN03472206
BioSample; SAMN10988110
Chemistry resources PharmacoDB; T3M10_1556_2019
Encyclopedic resources Wikidata; Q54971532
Gene expression databases ArrayExpress; E-MTAB-2770
Polymorphism and mutation databases IARC_TP53; 28362
LiGeA; CCLE_753
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number23