Cellosaurus logo
expasy logo

Cellosaurus SP-6.5 (CVCL_7997)

[Text version]
Cell line name SP-6.5
Synonyms SP 6.5; SP6.5; SP6_5
Accession CVCL_7997
Resource Identification Initiative To cite this cell line use: SP-6.5 (RRID:CVCL_7997)
Comments Omics: Transcriptomics; Microarray.
Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.
Sequence variations
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 77Y
Category Cancer cell line
Publications

PubMed=9154388; DOI=10.1076/ceyr.16.5.487.7047
Yolanda Diebold, Gonzalo Blanco, Maria Antonia Saornil-Alvarez, Nieves Fernandez, M. Carmen Lazaro;
Morphologic and immunocytochemical characterization of four human uveal cell lines (melanoma- and melanocytes-derived).
Curr. Eye Res. 16:487-495(1997)

PubMed=10892885
Alain Beliveau, Melanie Berube, Alain P. Rousseau, Guy Pelletier, Sylvain L. Guerin;
Expression of integrin alpha5beta1 and MMPs associated with epithelioid morphology and malignancy of uveal melanoma.
Invest. Ophthalmol. Vis. Sci. 41:2363-2372(2000)

PubMed=15645125; DOI=10.3892/ijo.26.2.405
Melanie Berube, Marieve Talbot, Charles Collin, Carine Paquet-Bouchard, Lucie Germain, Sylvain L. Guerin, Eric Petitclerc;
Role of the extracellular matrix proteins in the resistance of SP6.5 uveal melanoma cells toward cisplatin.
Int. J. Oncol. 26:405-413(2005)

PubMed=15714118; DOI=10.1097/00008390-200502000-00006
Rosario Lopez-Velasco, Antonio Morilla-Grasa, Maria Antonia Saornil-Alvarez, Jose L. Ordonez, Gonzalo Blanco, Guillermo Rabano, Nieves Fernandez, Ana Almaraz;
Efficacy of five human melanocytic cell lines in experimental rabbit choroidal melanoma.
Melanoma Res. 15:29-37(2005)

PubMed=17487557; DOI=10.1007/s10585-007-9072-z
Jean-Claude Marshall, Andre Nantel, Paula Blanco, Josee Ash, Stephanie R. Cruess, Miguel Noel Burnier Jr.;
Transcriptional profiling of human uveal melanoma from cell lines to intraocular tumors to metastasis.
Clin. Exp. Metastasis 24:353-362(2007)

PubMed=22236444; DOI=10.1111/j.1755-148X.2012.00971.x; PMCID=PMC3288394
Klaus Georg Griewank, Xiao-Xing Yu, Jahan S. Khalili, Mustafa Mert Sozen, Katherine Stemke-Hale, Chantale Bernatchez, Seth Wardell, Boris C. Bastian, Scott E. Woodman;
Genetic and molecular characterization of uveal melanoma cell lines.
Pigment Cell Melanoma Res. 25:182-187(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7997
Anatomy/cell type resources BTO; BTO_0002737
Encyclopedic resources Wikidata; Q54955390
Polymorphism and mutation databases Cosmic; 986620
Cosmic; 1628411
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number22